Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ZD-2138 is a potent and selective specific inhibitor of 5-lipoxygenase (5-LOX) that inhibits allergen-induced pulmonary bronchoconstriction and reduces neurally-induced fast-acting kallikrein-ergic constriction of isolated airways in guinea pigs.ZD-2138 can be used for the treatment of asthma disease.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 30,500 | |||
5 mg | 在庫あり | ¥ 73,500 | |||
10 mg | 在庫あり | ¥ 108,000 | |||
25 mg | 在庫あり | ¥ 177,500 | |||
50 mg | 在庫あり | ¥ 248,000 | |||
100 mg | 在庫あり | ¥ 335,000 | |||
500 mg | 在庫あり | ¥ 670,500 |
説明 | ZD-2138 is a potent and selective specific inhibitor of 5-lipoxygenase (5-LOX) that inhibits allergen-induced pulmonary bronchoconstriction and reduces neurally-induced fast-acting kallikrein-ergic constriction of isolated airways in guinea pigs.ZD-2138 can be used for the treatment of asthma disease. |
In vitro | The 5-lipoxygenase inhibitor ZD-2138 (1 μM) significantly inhibited these neurally mediated tachykinergic contractions, by approximately 50%, yet had no effect on the contractions evoked by stimulating tachykinergic fibers in an action potential-independent fashion with capsaicin or by exogenously applied neurokinin A.[1] |
別名 | Ici-D2138 |
分子量 | 397.44 |
分子式 | C23H24FNO4 |
CAS No. | 140841-32-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 15 mg/mL (37.74 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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ZD-2138 140841-32-3 Metabolism Lipoxygenase Ici-D2138 Ici-D-2138 Ici-D 2138 ZD2138 ZD 2138 Inhibitor inhibitor inhibit