| T1123 |
Camptothecin
|
7689-03-4
|
98%
|
|
|
Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity. Cam...
|
| TN2298 |
Vincosamide
|
23141-27-7
|
|
|
|
Vincosamide is an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity. Vincosamide can ...
|
| T5784 |
Topotecan
|
123948-87-8
|
98%
|
|
|
Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.
|
| T5S1952 |
9-Methoxycamptothecin
|
39026-92-1
|
98.49%
|
|
|
9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.
|
| T1174 |
Topotecan hydrochloride
|
119413-54-6
|
98.76%
|
|
|
Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.
|
| T4S1951 |
10-Methoxycamptothecin
|
19685-10-0
|
98.81%
|
|
|
10-Methoxycamptothecin possesses high anti-cancer activity.
|
| T3S1955 |
7-Ethylcamptothecin
|
78287-27-1
|
99.48%
|
|
|
1. 7-Ethylcamptothecin has the superior antitumor activity than CPT. (a). 7-Ethylcamptothecin has a stronger growth-inhibiting activity against tumor cells. (b)....
|
| T2764 |
(S)-10-Hydroxycamptothecin
|
19685-09-7
|
99.48%
|
|
|
(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
|
| T0486 |
Irinotecan hydrochloride trihydrate
|
136572-09-3
|
99.52%
|
|
|
Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.
|
| T1521 |
(±)-10-Hydroxycamptothecin
|
64439-81-2
|
99.58%
|
|
|
(±)-10-Hydroxycamptothecin (Hydroxy Camptothecine) is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selective...
|
| T6228 |
Irinotecan
|
97682-44-5
|
99.92%
|
|
|
Irinotecan (CPT-11), a derivative of camptothecin, is an inhibitor of DNA topoisomerase I (Topo I). Irinotecan has antitumor activity by preventing DNA strand re...
|
| T0486L |
Irinotecan Hydrochloride
|
100286-90-6
|
99.92%
|
|
|
Irinotecan Hydrochloride (CPT-11 hydrochloride) is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a...
|
| T1703 |
SN-38
|
86639-52-3
|
99.97%
|
|
|
SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM). SN-38 h...
|
| TN1176 |
10-Nitro-camptothecin
|
104195-61-1
|
98%
|
|
|
10-Nitro-camptothecin is a natural product
|
| TN2684 |
2,3,23-Trihydroxy-12-oleanen-28-oic acid
|
102519-34-6
|
98%
|
|
|
2β,3β,23α-Trihydroxy-12-oleanen-28-oic acid shows cytotoxic activities to human lung adenocarcinoma(A-549)cell lines. 2α,3β,23-Trihydroxyolean-12-en-28-oic acid ...
|
| TN2460 |
12-Ethyl-9-hydroxycamptothecin
|
119577-28-5
|
98%
|
|
|
12-Ethyl-9-hydroxycamptothecin is a natural product isolated from Camptotheca acuminata Decne
|
| T4952 |
9-Hydroxycamptothecin
|
67656-30-8
|
99.79%
|
|
|
9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.
|
