The terpenoids, sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenes. Most are multicyclic structures with oxygen-containing functional groups. About 60% of known natural products are terpenoids.
Plant terpenoids are used for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes. Well-known terpenoids include citral, menthol, camphor, salvinorin A in the plant Salvia divinorum, the cannabinoids found in cannabis, ginkgolide and bilobalide found in Ginkgo biloba, and the curcuminoids found in turmeric and mustard seed.
Many terpenes have biological activities and are used for the treatment of human diseases. The worldwide sales of terpene-based pharmaceuticals in 2002 were approximately US $12 billion. Among these pharmaceuticals, the anticancer drug Taxol and the antimalarial drug Artimesinin are two of the most renowned terpene-based drugs. All terpenoids are synthesized from two five-carbon building blocks. Based on the number of the building blocks, terpenoids are commonly classified as monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), and sesterterpenes (C25). These terpenoids display a wide range of biological activities against cancer, malaria, inflammation, and a variety of infectious diseases (viral and bacterial). In last two decades, natural-product bioprospecting from the marine environment has resulted in hundreds of terpenoids with novel structures and interesting bioactivities, with more to be discovered in the future. There is no doubt that more terpenoid-based clinical drugs will become available and will play a more significant role in human disease treatment in the near future.
Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
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T8247 | (+)-Aromadendrene | 489-39-4 |
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(+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria. | ||||
TN1420 | Bacopaside I | 382148-47-2 |
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Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer... | ||||
T3788 | Rehmannioside A | 81720-05-0 |
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Rehmannioside A is an iridoid glucoside extracted from traditional Chinese medicine Rehmannia. | ||||
T9279 | Nerolidol acetate | 2306-78-7 |
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Nerolidol acetate is a natural sesquiterpene with anti-cancer, anti-inflammatory, antibacterial and anti-insect activities. Nerolidol acetate can inhibit parasit... | ||||
T7190 | Actein | 18642-44-9 |
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Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblast... | ||||
T8295 | Sclareol glycol | 55881-96-4 |
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Sclareol glycol is the precursor of ambroxide. | ||||
T1246 | Bornyl acetate | 76-49-3 |
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Bornyl acetate (Isobornyl acetate) has an anti-inflammatory effect. It is the volatile ingredient in some Chinese traditional herbs and numerous conifer oils. | ||||
T3883 | Roburic acid | 6812-81-3 |
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Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2. | ||||
T3S2296 | Gardenoside | 24512-62-7 |
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Gardenoside has hepatoprotective, pain‑relieving, and anti-mastitis effects. it may be a potential therapeutic herb against NASH by suppressed supernatant ... | ||||
TN6738 | Orthosphenic acid | 86632-20-4 |
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Orthosphenic acid is a natural product isolated from M. triflora. | ||||
T3817 | Darutigenol | 5940-00-1 |
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Darutigenol has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion. | ||||
T71553 | Ainsliadimer A | 1039431-94-1 | 100% |
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Ainsliadimer A, a sesquiterpene lactone dimer from Ainsliaea macrocephala, has antitumour activity and induces cell death in various cancer cells. | ||||
T4672 | Brevilin A | 16503-32-5 | 100% |
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Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor a... | ||||
TN1568 | Deoxyartemisinin | 72826-63-2 | 100% |
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Deoxyartemisinin (2-deoxyartemisinin), a compound derived from Artemisia annua, has anti-inflammatory and anti-ulcer effects and is used in the study of malaria.... | ||||
T3797 | Isosilybin | 72581-71-6 | 100% |
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Isosilybin (Isosilibinin) and Silybin might be suitable candidates to design potent PXR antagonists to prevent drug-drug interactions via CYP3A4 in cancer patien... | ||||
T4S2326 | Cornuside | 131189-57-6 | 100% |
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1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in t... | ||||
TN1257 | 3-O-Acetyl-α-boswellic acid | 89913-60-0 | 100% |
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3-O-Acetyl-α-boswellic acid (α-Boswellic acid acetate) has strong anti-inflammatory activity. | ||||
T6S2023 | Harpagoside | 19210-12-9 | 100% |
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1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit li... | ||||
TN1745 | Hosenkoside M | 161016-51-9 | 100% |
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Hosenkoside M is a bazaine glycoside extracted from the balsam seeds of Hosenkoside. | ||||
T2902 | Costunolide | 553-21-9 | 100% |
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Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis. |