The fibroblast growth factor receptors (FGFR) are receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. The fibroblast growth factor receptors consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. The FGF/FGFR signalling pathway is involved in a variety of cancers.There are non-selective FGFR inhibitors that act on all of FGFR1-4 and other proteins, and some selective FGFR inhibitors for some/all of FGFR1-4. Selective FGFR inhibitors include AZD4547, BGJ398, JNJ42756493, and PD173074.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-03357 | FGFR2 Protein, Mouse, Recombinant (hFc)
FGFR2 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-00972 | FGFR2 Protein, Human, Recombinant (His & hFc)
FGFR2 Protein, Human, Recombinant (His & hFc)
|
Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-00423 | FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
|
Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-01011 | FGFR1 Protein, Human, Recombinant (His)
FGFR1 Protein, Human, Recombinant (His)
|
Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-02112 | FGFR4 Protein, Human, Recombinant (His)
FGFR4 Protein, Human, Recombinant (His)
|
Human | HEK293 |
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibro... | |||
TMPY-06034 | FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
|
Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-06036 | FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
|
Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-00341 | FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
|
Human | HEK293 |
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between membe... | |||
TMPY-04165 | FGFR3 Protein, Human, Recombinant (His)
FGFR3 Protein, Human, Recombinant (His)
|
Human | HEK293 |
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between membe... | |||
TMPY-06321 | FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
|
Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-06037 | FGFR4 Protein, Human, Recombinant (His), Biotinylated
FGFR4 Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 |
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibro... | |||
TMPY-06035 | FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
|
Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-06033 | FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
|
Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-05777 | FGFR1 Protein, Human, Recombinant (hFc)
FGFR1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-05761 | FGFR1 Protein, Human, Recombinant (His), Biotinylated
FGFR1 Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-04390 | FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
|
Human | Baculovirus-Insect Cells |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-04371 | FGFR1 Protein, Human, Recombinant (His & GST)
FGFR1 Protein, Human, Recombinant (His & GST)
|
Human | Baculovirus-Insect Cells |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-04273 | FGFR2 Protein, Human, Recombinant (aa 1-378, His)
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
|
Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-04200 | FGFR3 Protein, Human, Recombinant (hFc)
FGFR3 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between membe... | |||
TMPY-03926 | FGFR1 Protein, Rhesus, Recombinant (His)
FGFR1 Protein, Rhesus, Recombinant (His)
|
Rhesus | HEK293 |
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... |