Hematologic Malignancies Target Proteins

In hematological malignancies, CD19, BCMA, and CD22 are the most frequently studied target proteins. CD19 is the primary target for the treatment of B-cell blood cancers. BCMA and CD22 are both antigens expressed on the surface of B cells, and cell therapies targeting these two targets could be used to treat patients with B-cell blood cancers that have developed resistance to cell therapies targeting CD19. Other related targets under study include GPRC5D, CLEC12A and CD7.

カタログ番号	製品名 / Synonyms	Species	Expression System
TMPY-02263	Siglec-3/CD33 Protein, Mouse, Recombinant (hFc) Siglec-3/CD33 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
TMPY-02263	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and...
TMPY-02218	CD20 Protein, Ferret, Recombinant (His) CD20 Protein, Ferret, Recombinant (His)	Ferret	HEK293
TMPY-02218	CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent prot...
TMPY-02182	CD4 Protein, Ferret, Recombinant (His) CD4 Protein, Ferret, Recombinant (His)	Ferret	HEK293
TMPY-02182	T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-typ...
TMPY-02116	CD4 Protein, Human, Recombinant (aa 1-208, His) CD4 Protein, Human, Recombinant (aa 1-208, His)	Human	HEK293
TMPY-02116	T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-typ...
TMPY-01835	Syndecan-1 Protein, Mouse, Recombinant (His) Syndecan-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
TMPY-01835	Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expressio...
TMPY-01310	CD7 Protein, Mouse, Recombinant (His) CD7 Protein, Mouse, Recombinant (His)	Mouse	HEK293
TMPY-01310	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-01213	SLAMF7 Protein, Mouse, Recombinant (His) SLAMF7 Protein, Mouse, Recombinant (His)	Mouse	HEK293
TMPY-01213	SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a ...
TMPY-01211	BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc) BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293
TMPY-01211	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto...
TMPY-01158	CD38 Protein, Mouse, Recombinant (His) CD38 Protein, Mouse, Recombinant (His)	Mouse	HEK293
TMPY-01158	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-01093	CD10 Protein, Mouse, Recombinant (His) CD10 Protein, Mouse, Recombinant (His)	Mouse	HEK293
TMPY-01093	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-00966	BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc) BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
TMPY-00966	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto...
TMPY-00760	CD10 Protein, Human, Recombinant CD10 Protein, Human, Recombinant	Human	HEK293
TMPY-00760	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-00759	CD10 Protein, Human, Recombinant (hFc) CD10 Protein, Human, Recombinant (hFc)	Human	HEK293
TMPY-00759	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-00622	FOLR1 Protein, Canine, Recombinant (His) FOLR1 Protein, Canine, Recombinant (His)	Canine	HEK293
TMPY-00622	The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transpo...
TMPY-00543	FOLR1 Protein, Rat, Recombinant (His) FOLR1 Protein, Rat, Recombinant (His)	Rat	HEK293
TMPY-00543	The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transpo...
TMPY-00407	Siglec-2/CD22 Protein, Rat, Recombinant (His) Siglec-2/CD22 Protein, Rat, Recombinant (His)	Rat	HEK293
TMPY-00407	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface...
TMPY-00349	Siglec-2/CD22 Protein, Rhesus, Recombinant (His) Siglec-2/CD22 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
TMPY-00349	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface...
TMPY-00241	CD4 Protein, Rat, Recombinant (His) CD4 Protein, Rat, Recombinant (His)	Rat	HEK293
TMPY-00241	T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-typ...
TMPY-00158	Siglec-2/CD22 Protein, Rat, Recombinant (hFc) Siglec-2/CD22 Protein, Rat, Recombinant (hFc)	Rat	HEK293
TMPY-00158	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface...
TMPK-01310	Syndecan-1 Protein, Rabbit, Recombinant (His) Syndecan-1 Protein, Rabbit, Recombinant (His)	Rabbit	HEK293
TMPK-01310	CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix int...