Hematologic Malignancies Target Proteins

In hematological malignancies, CD19, BCMA, and CD22 are the most frequently studied target proteins. CD19 is the primary target for the treatment of B-cell blood cancers. BCMA and CD22 are both antigens expressed on the surface of B cells, and cell therapies targeting these two targets could be used to treat patients with B-cell blood cancers that have developed resistance to cell therapies targeting CD19. Other related targets under study include GPRC5D, CLEC12A and CD7.

カタログ番号	製品名 / Synonyms	Species	Expression System
TMPK-01300	Siglec-3/CD33 Protein, Cynomolgus, Recombinant (His) Siglec-3/CD33 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-01300	Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state....
TMPK-01284	Syndecan-1 Protein, Cynomolgus, Recombinant (His) Syndecan-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-01284	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteog...
TMPK-01258	SLAMF7 Protein, Cynomolgus, Recombinant (His) SLAMF7 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-01258	CD2-like receptor activating cytotoxic cells (CRACC), also known as CS1, novel Ly9, SLAMF7, and CD319, is a 65-75 kDa type I transmembrane glycoprotein in the SL...
TMPK-00846	Siglec-3/CD33 Protein, Human, Recombinant (aa 18-259, hFc) Siglec-3/CD33 Protein, Human, Recombinant (aa 18-259, hFc)	Human	HEK293
TMPK-00846	Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state....
TMPK-00845	Siglec-3/CD33 Protein, Human, Recombinant (His & Avi), Biotinylated Siglec-3/CD33 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00845	Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state....
TMPK-00844	Siglec-3/CD33 Protein, Human, Recombinant (His & Avi) Siglec-3/CD33 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00844	Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state....
TMPK-00843	Siglec-3/CD33 Protein, Human, Recombinant (His & Avi), FITC-Labeled Siglec-3/CD33 Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293
TMPK-00843	Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state....
TMPK-00595	Syndecan-1 Protein, Human, Recombinant (aa 23-254, His) Syndecan-1 Protein, Human, Recombinant (aa 23-254, His)	Human	HEK293
TMPK-00595	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteog...
TMPK-00594	Syndecan-1 Protein, Human, Recombinant (aa 23-254, hFc) Syndecan-1 Protein, Human, Recombinant (aa 23-254, hFc)	Human	HEK293
TMPK-00594	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteog...
TMPK-00593	Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00593	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteog...
TMPK-00572	ROR1 Protein, Canine, Recombinant (His) ROR1 Protein, Canine, Recombinant (His)	Canine	HEK293
TMPK-00572	ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family w...
TMPK-00413	ROR1 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi) ROR1 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi)	Human,Cynomolgus,Rhesus macaque	HEK293
TMPK-00413	ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family w...
TMPK-00346	CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi) CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00346	The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted ...
TMPK-00327	CD19 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) CD19 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus macaque	HEK293
TMPK-00327	CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses.Functions as coreceptor for the B-cell an...
TMPK-00282	CD4 Protein, Human, Recombinant (aa 26-390, His & Avi), Biotinylated CD4 Protein, Human, Recombinant (aa 26-390, His & Avi), Biotinylated	Human	HEK293
TMPK-00282	CD4, also known as L3T4, T4, and W3/25, is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset o...
TMPK-00281	CD4 Protein, Human, Recombinant (His & Avi) CD4 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00281	CD4, also known as L3T4, T4, and W3/25, is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset o...
TMPK-00225	SLAMF7 Protein, Human, Recombinant (His & Avi) SLAMF7 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00225	CD2-like receptor activating cytotoxic cells (CRACC), also known as CS1, novel Ly9, SLAMF7, and CD319, is a 65-75 kDa type I transmembrane glycoprotein in the SL...
TMPK-00201	Syndecan-1 Protein, Mouse, Recombinant (hFc) Syndecan-1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
TMPK-00201	Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteog...
TMPK-00184	CD20 Protein, Human, Recombinant (His & Avi), Biotinylated CD20 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
TMPK-00184	B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117...
TMPK-00183	CD20 Protein, Human, Recombinant (His & Avi) CD20 Protein, Human, Recombinant (His & Avi)	Human	E. coli
TMPK-00183	B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117...