Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins. The function of the immune system primarily depends on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by CD4 helper T-lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
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TMPJ-00074 | IL-18BP Protein, Human, Recombinant (hFc)
IL-18BP Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mo... | |||
TMPJ-00072 | IL-18BPd Protein, Mouse, Recombinant (hFc)
IL-18BPd Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, wh... | |||
TMPJ-00070 | IL-18 Protein, Human, Recombinant (His)
IL-18 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cyt... | |||
TMPJ-00062 | IL-22 Protein, Human, Recombinant (hIgG4 hFc)
IL-22 Protein, Human, Recombinant (hIgG4 hFc)
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Human | HEK293 Cells |
IL-22 Protein, Human, Recombinant (hIgG4 hFc) is expressed in HEK293 mammalian cells with C-hIgG4 Fc tag. The predicted molecular weight is 50-75 KDa and the acc... | |||
TMPJ-00061 | IL-22 Protein, Human, Recombinant (hIgG2 hFc)
IL-22 Protein, Human, Recombinant (hIgG2 hFc)
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Human | HEK293 Cells |
IL-22 Protein, Human, Recombinant (hIgG2 hFc) is expressed in HEK293 mammalian cells with C-hIgG2 Fc tag. The predicted molecular weight is 50-62 KDa and the acc... | |||
TMPJ-00060 | IL-25/IL17E Protein, Human, Recombinant (His)
IL-25/IL17E Protein, Human, Recombinant (His)
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Human | HEK293 Cells |
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins... | |||
TMPJ-00047 | IL-31 Protein, Human, Recombinant
IL-31 Protein, Human, Recombinant
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Human | E. coli |
Human Interleukin 31 (IL-31) is a cytokine containing a four-helix bundle structure. It shares several structural and functional characteristics with IL-6, Oncos... | |||
TMPJ-00046 | IL-17F Protein, Human, Recombinant
IL-17F Protein, Human, Recombinant
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Human | E. coli |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mi... | |||
TMPJ-00036 | IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 16-18 K... | |||
TMPJ-00034 | IL-4 Protein, Human, Recombinant (hFc)
IL-4 Protein, Human, Recombinant (hFc)
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Human | HEK293 Cells |
IL-4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40-55 KDa and the accession number... | |||
TMPJ-00030 | IL-1F10 Protein, Human, Recombinant
IL-1F10 Protein, Human, Recombinant
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Human | E. coli |
Human Interleukin 1 Family Member 10 (IL-1F10) is thought to participate in a network of Interleukin 1 cytokine family members to regulate adapted and innate imm... | |||
TMPJ-00020 | IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | HEK293 Cells |
IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5... |