T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature).After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus.CD4 and CD8 T cells are selected in the thymus, but undergo further differentiation in the periphery to specialized cells which have different functions. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" (cytotoxic) and CD4+ "helper" T cells. Regulatory T cells are yet another distinct population of T cells that provide the critical mechanism of tolerance, whereby immune cells are able to distinguish invading cells from "self".
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
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TMPY-05090 | CD25/IL2R alpha Protein, Rat, Recombinant (His)
CD25/IL2R alpha Protein, Rat, Recombinant (His)
|
Rat | Baculovirus-Insect Cells |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region,... | |||
TMPY-04289 | CD30L Protein, Cynomolgus, Recombinant (His)
CD30L Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 |
CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specif... | |||
TMPY-01226 | CD4 Protein, Mouse, Recombinant (His)
CD4 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-typ... | |||
TMPY-05260 | PD-1 Protein, Cynomolgus, Recombinant (His)
PD-1 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively reg... | |||
TMPY-01827 | CD30/TNFRSF8 Protein, Human, Recombinant (His)
CD30/TNFRSF8 Protein, Human, Recombinant (His)
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Human | HEK293 |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not... | |||
TMPY-05669 | CD8A & CD8B Heterodimer Protein, Human, Recombinant (Flag & His)
CD8A & CD8B Heterodimer Protein, Human, Recombinant (Flag & His)
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Human | HEK293 |
CD8A & CD8B Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 cells. | |||
TMPY-01103 | CD25/IL2R alpha Protein, Human, Recombinant (His)
CD25/IL2R alpha Protein, Human, Recombinant (His)
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Human | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region,... | |||
TMPY-01923 | CD25/IL2R alpha Protein, Mouse, Recombinant (His)
CD25/IL2R alpha Protein, Mouse, Recombinant (His)
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Mouse | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region,... | |||
TMPY-01180 | CD86 Protein, Human, Recombinant (His)
CD86 Protein, Human, Recombinant (His)
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Human | HEK293 |
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominan... | |||
TMPY-03203 | CD40 Protein, Rat, Recombinant (His)
CD40 Protein, Rat, Recombinant (His)
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Rat | HEK293 |
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential r... | |||
TMPY-01196 | CD3D Protein, Human, Recombinant (His)
CD3D Protein, Human, Recombinant (His)
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Human | HEK293 |
T-cell surface glycoprotein CD3 delta chain, also known as CD3D, is a single-pass type I membrane protein. CD3D, together with CD3-gamma, CD3-epsilon and CD3-zet... | |||
TMPY-01604 | CTLA-4 Protein, Mouse, Recombinant (His)
CTLA-4 Protein, Mouse, Recombinant (His)
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Mouse | HEK293 |
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is t... | |||
TMPY-01191 | CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293, His)
CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293, His)
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Human | HEK293 |
CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293,His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the... | |||
TMPY-02022 | CD40 Ligand Protein, Human, Recombinant (hFc)
CD40 Ligand Protein, Human, Recombinant (hFc)
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Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-01743 | 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)
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Human | HEK293 |
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necro... | |||
TMPY-04898 | PD-1 Protein, Human, Recombinant (hFc)
PD-1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively reg... | |||
TMPY-01423 | OX40/TNFRSF4 Protein, Human, Recombinant (His)
OX40/TNFRSF4 Protein, Human, Recombinant (His)
|
Human | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an ex... | |||
TMPY-01400 | CD4 Protein, Human, Recombinant (His)
CD4 Protein, Human, Recombinant (His)
|
Human | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-typ... | |||
TMPY-05384 | CD4 Protein, Human, Recombinant (hFc)
CD4 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-typ... | |||
TMPY-00864 | IL-6R Protein, Human, Recombinant (His)
IL-6R Protein, Human, Recombinant (His)
|
Human | HEK293 |
Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-... |