The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers. Members of this superfamily can be released from the cell membrane by extracellular proteolytic cleavage and function as a cytokine. These proteins are expressed predominantly by immune cells and they regulate diverse cell functions, including immune response and inflammation, but also proliferation, differentiation, apoptosis and embryogenesis. The superfamily contains 19 members that bind to 29 members of TNF receptor superfamily. The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain.The PROSITE pattern of this superfamily is located in a beta sheet in the central section of the protein that is conserved across all members.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-02202 | TNF alpha Protein, Rat, Recombinant
TNF alpha Protein, Rat, Recombinant
|
Rat | E. coli |
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule ... | |||
TMPY-01294 | TNF alpha Protein, Mouse, Recombinant
TNF alpha Protein, Mouse, Recombinant
|
Mouse | E. coli |
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule ... | |||
TMPJ-01391 | BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)
BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)
|
Mouse | Human Cells |
TNFSF13B/TNFSF20 belongs to the tumor necrosis factor family. It abundantly is expressed in peripheral blood Leukocytes and is specifically expressed in monocyte... | |||
TMPJ-00779 | TNF alpha Protein, Rabbit, Recombinant
TNF alpha Protein, Rabbit, Recombinant
|
Rabbit | E. coli |
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TN... | |||
TMPJ-00662 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
|
Human | E. coli |
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune s... | |||
TMPJ-00607 | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
|
Mouse | Human Cells |
Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in ... | |||
TMPJ-00603 | TL1A/TNFSF15 Protein, Mouse, Recombinant
TL1A/TNFSF15 Protein, Mouse, Recombinant
|
Mouse | E. coli |
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-sp... | |||
TMPJ-00139 | 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)
|
Human | E. coli |
Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1B... | |||
TMPJ-00137 | APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
|
Human | Human Cells |
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa... | |||
TMPY-03364 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant
RANKL/TNFSF11/CD254 Protein, Human, Recombinant
|
Human | HEK293 |
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TR... | |||
TMPY-00033 | 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfam... | |||
TMPY-03956 | Fas Ligand Protein, Human, Recombinant (His)
Fas Ligand Protein, Human, Recombinant (His)
|
Human | Yeast |
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is... | |||
TMPY-05365 | BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated
|
Human | HEK293 |
B lymphocyte stimulator (BLyS), also known as TNFSF13B, CD257 and BAFF, is a single-pass type II membrane protein, which belongs to the tumor necrosis factor fam... | |||
TMPY-01920 | BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
|
Human | HEK293 |
B lymphocyte stimulator (BLyS), also known as TNFSF13B, CD257 and BAFF, is a single-pass type II membrane protein, which belongs to the tumor necrosis factor fam... | |||
TMPY-02153 | TNF beta Protein, Human, Recombinant
TNF beta Protein, Human, Recombinant
|
Human | E. coli |
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs ... | |||
TMPY-04832 | OX40L/TNFSF4 Protein, Human, Recombinant (hFc)
OX40L/TNFSF4 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecul... | |||
TMPY-04146 | TNF alpha Protein, Human, Recombinant (hFc)
TNF alpha Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule ... | |||
TMPY-03645 | BAFF/TNFSF13B Protein, Cynomolgus, Recombinant (hFc)
BAFF/TNFSF13B Protein, Cynomolgus, Recombinant (hFc)
|
Cynomolgus | HEK293 |
B lymphocyte stimulator (BLyS), also known as TNFSF13B, CD257 and BAFF, is a single-pass type II membrane protein, which belongs to the tumor necrosis factor fam... | |||
TMPY-02726 | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc)
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TR... | |||
TMPY-04645 | TL1A/TNFSF15 Protein, Human, Recombinant (hFc)
TL1A/TNFSF15 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A... |