CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 29.73 kDa and the accession number is A0A8J8XUI3.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 約5 days | ¥ 112,000 |
500 μg | 約5 days | ¥ 447,500 |
1 mg | 約5 days | ¥ 746,000 |
説明 | CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 29.73 kDa and the accession number is A0A8J8XUI3. |
Species | Cynomolgus |
Expression Host | HEK293 Cells |
Tag | C-mFc |
Accession Number | A0A8J8XUI3 |
別名 | GPR-CY6, CY6, CKRL1, CDw198, CMKBR8, ChemR1, CKR-L1, CD198, CCR-8, TER-1, CCR8, CMKBRL2, TER1, GPRCY6 |
Construction | Met1-Lys35 |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | 29.73 kDa (predicted). Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CCR8 Protein, Cynomolgus, Recombinant (mFc) CMKBRL-2 GPR-CY6 TER 1 CD-198 CY6 CKRL1 CDw198 CY 6 GPRCY-6 CKRL-1 CMKBR8 CD 198 ChemR1 CMKBR-8 CMKBRL 2 CKR-L1 CD198 CY-6 GPRCY 6 CKRL 1 CCR-8 CCR 8 TER-1 CCR8 CMKBR 8 CMKBRL2 TER1 GPRCY6 recombinant recombinant-proteins proteins protein