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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T2386 | Pirfenidone | S-7701,AMR-69,S-7701,AMR69 | CCR , TGF-beta/Smad |
Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tum... | |||
T12485 | Pirfenidone-d5 | AMR69 D5,Pirfenidone D5 | Others |
Pirfenidone D5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. | |||
T15300 | Fluorofenidone | AKF-PD | Others |
Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an an... |