16
6
6
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T76208 | Arginase | ||
Arginase is an enzyme of the urea cycle. Arginase catalyzes the hydrolysis of L-arginine to L-ornithine and urea [1] . | |||
T10367 | Arginase inhibitor 1 | Others | |
Arginase inhibitor 1 is a potent inhibitor of human arginases I and II (IC50s: 223 and 509 nM). | |||
T6779 | BEC hydrochloride | BEC HCl | Arginase |
BEC hydrochloride (BEC HCl) is a competitive arginase inhibitor, which bind slowly. Ki of BEC HCl is 0.31 μM (pH7.5) for Arginase II, and is 0.4-0.6 μM for rat Arginase I. | |||
T12240 | Nor-NOHA acetate | Nω-Hydroxy-nor-L-arginine acetate | Apoptosis , Arginase |
nor-NOHA acetate (Nω-Hydroxy-nor-L-arginine acetate) is a reversible inhibitor of arginase, with anti-leukemic activity, effective in endothelial dysfunction, immunosuppression, and metabolism. | |||
T9096 | Nω-Hydroxy-nor-L-Arginine Dihydrochloride | Arginase | |
Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a competitive and reversible inhibitor of arginase | |||
T39766 | Nor-NOHA monoacetate | Nor NOHA monoacetate,Nω-Hydroxy-nor-L-arginine monoacetate | Arginase |
nor-NOHA monoacetate (Nω-Hydroxy-nor-L-arginine) is a highly potent and selective arginase inhibitor. nor-NOHA monoacetate inhibits rat hepatic arginase and inhibits the hydrolysis of L-arginine, which can be used to stu... | |||
T12206 | NED-3238 | Others | |
NED-3238 is a highly potent inhibitor of arginase I and II (IC50 of 1.3 nM and 8.1 nM, respectively). | |||
T10692L | Numidargistat | INCB01158,CB-1158 | Others |
CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2). | |||
T10692 | CB-1158 dihydrochloride (2095732-06-0 free base) | INCB01158 dihydrochloride,CB-1158 dihydrochloride | Others |
CB-1158 dihydrochloride is an effective and orally active inhibitor of arginase (IC50s: 86 nM and 296 nM for recombinant human arginase 1 and 2). | |||
T26516 | ABH Hydrochloride | 6-borono-L-norleucine,ABH HCl | |
ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses. | |||
T61336 | Numidargistat dihydrochloride | ||
Numidargistat dihydrochloride (CB-1158) is a highly potent and orally active chemical compound that effectively inhibits arginase. It exhibits IC50 values of 86 nM and 296 nM for recombinant human arginase 1 and 2, respe... | |||
T39932 | ARG1-IN-1 | ARG1-IN-1 | |
ARG1-IN-1 is a human arginase 1 inhibitor with an IC 50 of 29 nM. | |||
T70367 | SNU-BP | ||
SNU-BP is an agonist of PPAR-gamma, inhibiting lipopolysaccharide (LPS)-induced NO production and pro-inflammatory cytokines. SNU-BP potentiates interleukin-4-induced arginase-1 expression, and promotes microglial polari... | |||
T78656 | ARG1-IN-1 hydrochloride | Arginase | |
ARG1-IN-1 hydrochloride is a potent inhibitor of human arginase 1, exhibiting an IC50 value of 29 nM [1]. | |||
T70928 | CB-1158-analog | ||
CB-1158-analog, also known as Numidargistat-analog and INCB01158-analog, is a potent and orally active arginase inhibitor with IC50=89 nM) . CB-1158 blocked myeloid cell-mediated suppression of T cell proliferation in vi... | |||
T83779 | EP4 Antagonist 14 | Prostaglandin E2 Receptor 4 Antagonist 14,PGE2 Receptor 4 Antagonist 14 | |
EP4 antagonist 14 is a prostaglandin E2 receptor subtype EP4 antagonist, demonstrating an IC50 of 1.1 nM in a HEK293 human receptor reporter assay and blocking β-arrestin recruitment due to PGE2 with an IC50 of 0.9 nM. A... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T11054 | DL-Norvaline | 2-Aminopentanoic acid | Arginase , Endogenous Metabolite |
DL-Norvaline (2-Aminopentanoic acid) is a non-competitive inhibitor of arginase. | |||
T3S0401 | Piceatannol 3'-O-glucoside | Piceatannol 3-glycoside,Quzhaqigan | Arginase , NO Synthase |
Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lung injury. | |||
T4788 | L-Norvaline | Others , Endogenous Metabolite | |
L-Norvaline is an arginase inhibitor and a non-proteinogenic branched-chain amino acid. L-Norvaline has previously been reported to be a natural component of an antifungal peptide of Bacillus subtilis. L-Norvaline and ot... | |||
T38241 | 2-Aminoimidazole | ||
2-Aminoimidazole is a potent antibiofilm agent and adjuvant to antimicrobial treatments, which effectively disrupts bacterial self-protection mechanisms by inhibiting biofilm formation and genetically-encoded antibiotic ... | |||
TN6456 | N-trans-caffeoyloctopamine | ||
N-trans-Caffeoyltyramine has both arginase inhibitory property and antioxidant capacity. | |||
T11802 | L-Canaline | Others | |
L-Canaline, a nonprotein amino acid found in many leguminous plants, exhibits potent anticancer and antiproliferative effects. It effectively inhibits the growth of the malaria parasite Plasmodium falciparum with an IC50... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-02526 | Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth... | |||
TMPY-02168 | Arginase 1/ARG1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Arginase 1/ARG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is P05089-1. | |||
TMPH-02524 | Arginase-1/ARG1 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ... | |||
TMPH-02525 | Arginase-1/ARG1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Arginase-1/ARG1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 50.8 kDa and the accession number is Q61176. | |||
TMPY-04685 | Arginase 1/ARG1 Protein, Human, Recombinant (His & MYC) | Human | HEK293 Cells |
Arginase 1/ARG1 Protein, Human, Recombinant (His & MYC) is expressed in HEK293 mammalian cells with His and MYC tag. The predicted molecular weight is 36.7 kDa and the accession number is P05089-1. | |||
TMPJ-01058 | ARG2 Protein, Human, Recombinant (His) | Human | E. coli |
Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not found... |