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Search Results for " C5b "

ターゲット

6

阻害剤

14

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T9915 Eculizumab Complement System
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
T64611 Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R
Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb #9649R is a useful organic compound for research related to life sciences and the catalog number is T64611.
T74551 Avacincaptad pegol sodium
Avacincaptad pegol (ARC1905), an anti-C5 RNA aptamer, prevents the cleavage of complement factor 5 (C5) into fragments C5a and C5b. It is currently under investigation for the treatment of age-related macular degeneratio...
T74552 Non-PEGylated/naked ARC1905
ARC1905, a non-PEGylated/naked anti-C5 RNA aptamer, functions by inhibiting the cleavage of complement factor 5 (C5) into its components, C5a and C5b, without PEG conjugation. This compound is currently being researched ...
T31877 Freselestat ONO-PO 736,ONO-6818,ONO 6818,ONO6818
Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9. Freselestat reduces inflammatory mediators during simulated cardiopulmonary bypass.
T77190 Crovalimab
Crovalimab (SKY59; RO7112689) is a novel humanized antibody designed to target C5 in a pH-dependent manner, demonstrating binding affinities (KD) of 15.2 nM and 16.8 μM at pH levels of 7.4 and 5.8, respectively. Addition...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-05057 Complement C5 Protein, Human, Recombinant (His & FLAG) Human HEK293
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-00653 Complement C5 Protein, Human, Recombinant (Complement C5a) Human E. coli
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-06814 Complement C5 Protein, Human, Recombinant (Flag) Human HEK293
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-04133 UNC5B Protein, Human, Recombinant (His) Human HEK293
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-00507 UNC5B Protein, Human, Recombinant (hFc) Human HEK293
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPH-01709 Mucin-5B/MUC5B Protein, Human, Recombinant (His & Myc) Human E. coli
Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus.
TMPY-04003 UNC5B Protein, Rat, Recombinant (hFc) Rat HEK293
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPJ-00585 Complement C8 gamma Protein, Human, Recombinant (His) Human E. coli
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 ...
TMPH-03270 Complement C5 Protein, Rat, Recombinant (His & Myc) Rat E. coli
Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the founda...
TMPY-03004 CD55/DAF Protein, Rat, Recombinant (hFc) Rat HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-02616 CD55/DAF Protein, Mouse, Recombinant (His) Mouse HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-01292 CD55/DAF Protein, Human, Recombinant (His) Human HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-00713 CD55/DAF Protein, Human, Recombinant (hFc) Human HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-06679 CD55/DAF Protein, Mouse, Recombinant (hFc) Mouse HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...