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Search Results for " CCR3 "

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天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T10156	CCR3 antagonist 1		CCR
	CCR3 antagonist 1 is a potent CCR3 antagonist, used for the research of inflammatory and immunologic diseases.		CCR
T11699	J-113863		CCR
	J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptor...		CCR
T4674	SB297006	SB 297006	CCR
	SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ...		CCR
T23321	SB 328437	(S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate,ZINC29222893	CCR
	SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).		CCR
T11521	GW 766994	GW 994	CCR
			CCR
T30535	BMS-639623	UNII-PON9OFP69G,PON9OFP69G,BMS 639623,CHEMBL399495
	BMS-639623 is a CCR3 antagonist with a picomolar inhibitory effect on eosinophilic chemotaxis and can be used in the treatment of asthma.
T36620	ALK4290	ALK4290
	ALK4290 (AKST4290) is a potent and orally actively CCR3 inhibitor, compound Example 2, with a Ki of 3.2 nM for hCCR3[1]. ALK4290 can be used for the research of neovascular age-related macular degeneration and Parkinsoni...
T30865	CH-0076989	UNII-9E629B19WL,CHEMBL485834,9E629B19WL,CH 0076989
	CH-0076989 is a chemokine receptor CCR3 agonist.
T23492	UCB 35625		Others
	chemokine CCR1 and CCR3 receptor antagonist		Others
T76504	CKLF1-C19
	CKLF1-C19, the C-terminal peptide of human chemokine-like factor 1 (CKLF1), interacts with CCR4 and inhibits chemotaxis induced by CKLF1 and CCL17. It also suppresses allergic lung inflammation by inhibiting chemotaxis m...

Compounds

Synonym: (S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate,ZINC29222893

Synonym: UNII-PON9OFP69G,PON9OFP69G,BMS 639623,CHEMBL399495

Synonym: UNII-9E629B19WL,CHEMBL485834,9E629B19WL,CH 0076989

カタログ番号	製品名	別名	ターゲット
T75499	Maceneolignan H
	Maceneolignan H (Compound 8), a neolignane derived from the arils of Myristica fragrans, acts as a selective CCR3 antagonist with an EC 50 value of 1.4 μM. This compound shows promise for allergic disease research [1].

天然物製品

Recombinant Proteins

Species：

Expression System：

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カタログ番号	製品名	Species	Expression System
TMPJ-01001	CCL11 Protein, Human, Recombinant	Human	E. coli
	C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of all...
TMPK-01196	CCL24 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fib...
TMPJ-00019	CCL28 Protein, Human, Recombinant	Human	E. coli
	Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and i...
TMPK-01265	CCL24 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fib...
TMPK-00704	CCL24 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fib...
TMPK-01195	CCL24 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fib...
TMPJ-01341	CCL24 Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58% amino acid sequence identity with human Cc...
TMPJ-00873	CCL3L1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including che...
TMPY-02795	Eotaxin-2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in imm...
TMPJ-00993	CCL5 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. CCL5 is secreted by many cell types at inflammatory s...
TMPJ-00831	CCL3 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, ...
TMPY-05353	CCL26 Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3),...
TMPY-03728	CCL28 Protein, Human, Recombinant (His)	Human	E. coli
	CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal su...
TMPY-00564	MCP-4 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family ...