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Search Results for " CXXC5 "

ターゲット

4

阻害剤

カタログ番号	製品名	別名	ターゲット
T39508	KY-02327		Others
	KY-02327, a metabolically stabilized analog of KY-02061, serves as a potent inhibitor of the Dishevelled (Dvl)-CXXC5 interaction. This compound activates the Wnt/β-catenin pathway, thereby promoting osteoblast differenti...		Others
T9025	KY19382	2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382,A3051	Others , GSK-3 , Wnt/beta-catenin
	KY19382 (2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382) is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of 19 and 10 nM, respectively). It...		Others , GSK-3 , Wnt/beta-catenin
T40950	A3334
	A3051, is a robust and orally active inhibitor of CXXC5-DVL with an IC 50 of 63.06 nM. Its applications include research into phenotypes associated with obesity, diabetes, and NASH that are induced by high fat diet (HFD)...
T62436	KY-02327 acetate
	KY-02327 acetate is a potent inhibitor of Dishevelled (Dvl)-CXXC5 interactions and is a metabolically stable analog of KY-02061. KY-02327 acetate activates the Wnt/β-catenin pathway, which in turn promotes osteoblast dif...

Compounds

Synonym: 2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382,A3051

Target: Others, GSK-3, Wnt/beta-catenin

KY-02327 acetate

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