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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5995 | Larotrectinib | LOXO-101,ARRY-470 | Apoptosis , Trk receptor |
Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase and is highly selective only for the TRK family of receptors(IC50s = 2-20 nM). | |||
T6880 | Larotrectinib sulfate | LOXO-101 sulfate,Larotrectinib (LOXO-101) sulfate,Larotrectinib,LOXO-101 (sulfate),ARRY-470,ARRY-470 (sulfate) | Apoptosis , Trk receptor |
Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). | |||
T62341 | (R)-Larotrectinib | ||
(R)-Larotrectinib is a potent inhibitor of TRK and acts on TrkA (IC50: 28.5 nM). (R)-Larotrectinib can be used to study cancer, inflammation and certain infectious diseases. |