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Search Results for " MLL-r "

ターゲット

Apoptosis Histone Methyltransferase

3

阻害剤

カタログ番号	製品名	別名	ターゲット
T8838	CCI-007		Apoptosis , Histone Methyltransferase
	CCI 007 is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485		Apoptosis , Histone Methyltransferase
T12943	SNDX-5613		Epigenetic Reader Domain , Histone Methyltransferase
	SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM). SNDX-5613 can be used for the research of MLL-rearranged (MLL-r) acute leukemias.		Epigenetic Reader Domain , Histone Methyltransferase
T10706	CCI-006		Mitochondrial Metabolism
	CCI-006, a selective inhibitor and chemosensitizer for MLL-rearranged leukemia cells, disrupts mitochondrial respiration. This action leads to irreversible mitochondrial depolarization and triggers a pro-apoptotic unfold...		Mitochondrial Metabolism

Compounds

Target: Apoptosis, Histone Methyltransferase

Target: Epigenetic Reader Domain, Histone Methyltransferase

Target: Mitochondrial Metabolism

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