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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T30778 | CCG-257081 | MRTF/SRF-IN-1,CCG257081,CCG 257081 | Rho , Ras |
CCG-257081 (MRTF/SRF-IN-1) is an inhibitor of cardiac myosin-related transcription factor and serum response factor (MRTF/SRF) that acts by inhibiting the Rho/MRTF/SRF pathway.CCG-257081 has shown efficacy in preventing ... | |||
T22062 | CCG-100602 | Rho , Ras | |
CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM). | |||
T4306 | CCG-203971 | CCG203971 | Rho , Ras |
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also inhibits PC-3 cell migration (IC50: 4.2 μM),... | |||
T7764 | CCG-222740 | ROCK , Rho , Ras | |
CCG-222740 is an inhibitor of Rho/MRTF pathway | |||
T26967 | CCG-232601 | CCG 232601,CCG232601 | |
CCG-232601 is a inhibitor of the Rho/MRTF/SRF transcriptional pathway. | |||
T82766 | CCG-232964 | ROCK | |
CCG-232964 is an orally active Rho/MRTF/SRF inhibitor that suppresses LPA-induced CTGF gene expression [1]. | |||
T68431 | CCG-58150 | ||
CCG-58150 is a potentiInhibitor of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma. | |||
T23221 | (R)-CCG-1423 | Others | |
(R)-CCG-1423 is a stereoisomer of CCG-1423. CCG-1423 is a Rho inhibitor involved in blocking signaling through myocardin-related transcription factor A (MRTF-A) and serum response factor (SRF). |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-01724 | MRTFA Protein, Human, Recombinant (His & KSI) | Human | E. coli |
Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF... |