ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T3513 | GSK180736A | 817194-38-0 | 98% |
|
| GSK180736A is an effective and selective GRK2 inhibitor (IC50: 0.77 μM) and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA (IC50: 30 μM), b... | ||||
| T6057 | URMC-099 | 1229582-33-5 | 98% |
|
| URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM)... | ||||
| T10358 | Netarsudil Dihydrochloride | 1253952-02-1 | 98% |
|
| Netarsudil hydrochloride is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP... | ||||
| T12747 | ROCK2-IN-2 | 1995065-79-6 | 98% |
|
| ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM). | ||||
| T26078 | Rhodblock 6 | 886625-06-5 | 98% |
|
| Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits the localization of phosphorylated MRLC (Myosin Regulatory Light Chain) and acts by specifically inhib... | ||||
| T77609 | WAY-656935 | 852902-81-9 | 98% |
|
| WAY-656935 inhibits ROCK. | ||||
| T36196 | CAY10746 | 2247240-76-0 | 98% |
|
| CAY10746 is a selective Rho kinase (ROCK) inhibitor that inhibits ROCK I and ROCK II with IC50 values of 0.014 μM and 0.003 μM, respectively.CAY10746 can be used... | ||||
| T6321 | Tofacitinib | 477600-75-2 | 98% |
|
| Tofacitinib is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis. | ||||
| T4488 | GSK-25 | 874119-56-9 | 98% |
|
| GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically impr... | ||||
| T3060 | Fasudil hydrochloride | 105628-07-7 | 98% |
|
| Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively. | ||||
| T1606 | Fasudil | 103745-39-7 | 98% |
|
| Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK. | ||||
| TQ0319 | Ripasudil | 887375-67-9 | 98% |
|
| Ripasudil (K-115) hydrochloride dihydrate is a specific ROCK inhibitor (IC50s: 51/19 nM for ROCK1/ROCK2). | ||||
| T7885 | Afuresertib hydrochloride | 1047645-82-8 | 98% |
|
| Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively) | ||||
| T19913 | CKI-7 | 1177141-67-1 | 98% |
|
| CKI-7 2HCl is an inhibitor of casein kinase 1 (CK1). | ||||
| T9652 | SB-747651A Dihydrochloride | 1781882-72-1 | 98% |
|
| SB-747651A dihydrochloride is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor with an IC 50 of 11 nM. SB-747651A dihydrochloride also ... | ||||
| T6867 | Belumosudil | 911417-87-3 | 98% |
|
| KD025 is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM). | ||||
| TQ0110 | ROCK-IN-2 | 867017-68-3 | 98% |
|
| Azaindole 1 is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2. | ||||
| T2633 | GSK429286A | 864082-47-3 | 98% |
|
| GSK429286A is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM). | ||||
| T7301 | BDP5290 | 1817698-21-7 | 98% |
|
| BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.) | ||||
| T23308 | SAR407899 hydrochloride | 923262-96-8 | 98% |
|
| ATP-competitive ROCK inhibitor | ||||
