ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T9986 | (E/Z)-ZINC09659342 | 591726-26-0 | 98% |
|
| (E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction. | ||||
| T24833 | ZINC69391 | 303094-67-9 | 98% |
|
| ZINC69391 is a selective inhibitor of Rac1 with antiproliferative and antimetastatic effects. ZINC69391 interferes with the interaction of Rac1 with Dock180, red... | ||||
| T14004 | 1A-116 | 1430208-73-3 | 98% |
|
| 1A-116 is a specific inhibitor of Rac1 . | ||||
| T6483 | EHT 1864 | 754240-09-0 | 98% |
|
| EHT 1864 is a effective Rac family GTPase inhibitor for Rac1/Rac1b/Rac2/Rac3 (Kd: 40/50/60/250 nM). | ||||
| T2014 | CCG-1423 | 285986-88-1 | 98% |
|
| CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription. | ||||
| T6739 | Zoledronic Acid | 118072-93-8 | 98% |
|
| Zoledronate is a bisphosphonate. Zometa is used to prevent skeletal fractures in patients with cancers such as multiple myeloma and prostate cancer. It can also ... | ||||
| T2427 | EHop-016 | 1380432-32-5 | 98% |
|
| EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3. | ||||
| T24642 | YH-306 | 1373764-75-0 | 98% |
|
| YH-306 is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis. | ||||
| T8473 | MLS000532223 | 16616-39-0 | 98% |
|
| MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM). | ||||
| T3553 | Y16 | 429653-73-6 | 98% |
|
| Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated sign... | ||||
| T26193 | SKLB-163 | 1255099-06-9 | 98% |
|
| SKLB-163 is an anticancer agent that acts by downregulating RhoGDI, decreasing phosphorylated Akt and p44/42 MAPK, and activating JNK-1 signaling pathway and cas... | ||||
| T61448 | AZA1 | 1071098-42-4 | 98% |
|
| AZA1 is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induced apoptosis of prostate cancer cells and inhibited cell proliferation, migration and invasion. | ||||
| T7764 | CCG-222740 | 1922098-69-8 | 98% |
|
| CCG-222740 is an inhibitor of Rho/MRTF pathway | ||||
| T4306 | CCG-203971 | 1443437-74-8 | 98% |
|
| CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This... | ||||
| T16745 | Rhosin hydrochloride | 1281870-42-5 | 98% |
|
| Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0... | ||||
| TP2131L | Rac1 Inhibitor W56 acetate(1095179-01-3 free base) | TP2131L | 98% |
|
| Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with... | ||||
| T15602 | ITX3 | 347323-96-0 | 98% |
|
| ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM. ITX3 has anticancer effects, inhibits trion mediated GTP exchange ... | ||||
| T25450 | GGTI 2147 | 191102-87-1 | 98% |
|
| GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis. | ||||
| T6342 | NSC 23766 trihydrochloride | 1177865-17-6 | 98% |
|
| NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related targets, RhoA or Cdc42. | ||||
| T22991 | ML-099 | 496775-95-2 | 98% |
|
| pan activator of Ras-related GTPases | ||||
