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T0994 |
Ketotifen fumarate
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HC 20511 fumarate |
PDE
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Histamine Receptor
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Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. |
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T62656 |
GPR81 agonist 1
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GPR
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GPR81 agonist 1 is a potent and selective GPR81 agonist with high affinity for human and mouse GPR81.GPR81 agonist 1 inhibits lipolysis of differentiated 3T3-L1 adipocytes, improves insulin sensitivity and glycaemic cont... |
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T72536 |
GPR84 antagonist 2
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GPR84 Antagonist 2, a potent and selective GPR84 antagonist (IC 50 = 8.95 nM), demonstrates oral activity and significantly enhances potency in calcium mobilization assays. It effectively inhibits neutrophil and macropha... |
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T11462 |
GPR84 antagonist 8
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GPR
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T62261 |
GPR84 antagonist 1
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GPR84 antagonist 1 is a highly selective, high-affinity competitive antagonist of human GPR84. |
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T79902 |
GPR88 agonist 2
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GPR88 agonist 2 (compound 53) serves as a potent, brain-penetrant agonist of GPR88, exhibiting an EC50 of 14 µM in the GPR88 cAMP functional assay [1]. |
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T79901 |
GPR88-IN-1
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GPR88-IN-1 is a GPR88 antagonist that may be utilized for the study of central nervous system disorders [1]. |
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T72772 |
GPR81 agonist 2
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GPR81 agonist 2 is a potent agonist targeting the GPR81 receptor, demonstrating EC50 values of 0.023 µM for hGPR81 and 0.123 µM for hGPR109A, respectively. |
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T62918 |
GPR84 antagonist 3
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GPR84 Antagonist 3 (compound 42), a potent inhibitor of the G-protein-coupled receptor 84 (GPR84), exhibits a pIC50 value of 8.28, indicating strong antagonistic activity by inhibiting GTPγS. Additionally, it possesses a... |
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T36739 |
Prednisone 21-aldehyde/22-hydroxy Prednisone
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Prednisone 21-aldehyde is a derivative of the synthetic corticosteroid prednisone that has antiviral activity against influenza virus A-PR8 in embryonated chicken eggs. 22-hydroxy Prednisone is an unstable adduct of pred... |
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T37466 |
CAY10766
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CAY10766 is an antiviral compound.1It inhibits entry of influenza virus-like particles pseudotyped with hemagglutinin A (HA) from H5N1 influenza A virus into A549 cells (EC50= 0.24 μM). CAY10766 (1 μM) reduces H1N1 and H... |
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T80279 |
Urumin
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Influenza Virus
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Urumin, a compound with antiviral properties, inhibits human influenza A virus growth, particularly the PR8 strain, with an inhibitory concentration (IC 50) of 3.8 μM. It acts by targeting the conserved stalk of H1 hemag... |
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T15625 |
JNJ4796
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Others
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JNJ4796 is an oral active fusion inhibitor of the influenza virus, by inhibiting hemagglutinin (HA)-mediated fusion to neutralizing the influenza A group 1 virus. JNJ4796 mimics the functionality of the broadly neutraliz... |
