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GPR

G-protein coupled receptors (GPRs) are a family of seven-transmembrane receptors, which play an important role in the response to peptide hormones, neurotransmitters, and free fatty acids.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T14211 AMG-009 1027847-67-1 98%
AMG-009 is a selective and potent dual antagonist of CRTH2 and DP, with an IC50 value of 3 nM for CRTH2 and 12 nM for DP receptors.
T22986 MK 1903 1268882-43-4 98%
MK 1903 is a potent and selective complete agonist for the hydroxy-carboxylic acid receptor 2 (HCA2). HCA2 is also known as G protein-coupled receptor 109A(GPR10...
TN1849 Kuwanon H 76472-87-2 98%
Kuwanon H, and possibly kuwanon G also, are specific antagonists for the gastrin-releasing peptide (GRP) -preferring receptor and can be useful for studying the ...
T12216 NF-56-EJ40 2380230-73-7 98%
NF-56-EJ40 is an effective and highly selective antagonist of human SUCNR1 with an IC50 of 25 nM and a Ki of 33 nM.
TP1345 Kisspeptin-10, human (TFA)(374675-21-5,FREE) 98%
Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor ...
T15448 GW-1100 306974-70-9 98%
GW-1100 is a selective GPR40 and FFAR1 antagonist for the study of diabetes and metabolic diseases.
T1781 GW9508 885101-89-3 98%
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
T15413 GPR120 Agonist 3 1599477-75-4 98%
GPR120 Agonist 3 (GPR120-IN-1) is a selective agonist of Gpr120 ( logEC50: -7.62).
TP1928L1 [Orn5]-URP acetate 98%
[Orn5]-URP acetate is an effective and selective Urotensin-II receptor (UT) antagonist (pEC50 = 7.24). [Orn5]-URP exhibits no agonist activity.
TQ0241 TUG-770 1402601-82-4 98%
TUG-770 is a GPR40/FFA1 agonist with potential anti-inflammatory activity.TUG-770 can be used to study type 2 diabetes, dementia, and Alzheimer's disease.
T37526 2-Oleoylglycerol 3443-84-3 98%
2-Oleoylglycerol is a lipid found in palm kernel, sunflower seed and rice bran.2-Oleoylglycerol acts as a GPR119 agonist with neuroprotective effects and induces...
T84313 OX04528 3028055-45-7 98%
OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research.
T60074 GPCR agonist-2 291528-35-3 98%
GPCR agonist-2 (4-(Cyclopropylamino)-3-nitrobenzoic acid) is an agonist of the orphan human GPCR GPR109B.
T5351L PU-WS13 hydrobromide 98%
PU-WS13 hydrobromide is a GRP94 inhibitor with anti-inflammatory activity and inhibits the proliferation of M2-like macrophages in mouse TNBC tumors.
T36036 CAY10786 1239987-91-7 98%
CAY10786 (GPR52 antagonist-1) is an antagonist of G protein-coupled receptor 52 (GPR52, IC50 = 0.63 μM).
T7359 CAY10471 Racemate 844639-57-2
CAY10471 Racemate (TM30089 Racemate) is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 Racemate binds to the human CRTH2/DP2, DP1, and TP re...
T1286 Vincamine 1617-90-9
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly...
T7127 DC260126 346692-04-4
DC260126 is a small-molecule antagonist of FFA1 (GPR40)
T5406 SNAP 94847 487051-12-7
SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces ...
T2351 Fasiglifam 1000413-72-8
Fasiglifam (TAK875) is a potent, selective and orally bioavailable GPR40 agonist.
AMG-009
T14211
AMG-009 is a selective and potent dual antagonist of CRTH2 and DP, with an IC50 value of 3 nM for CRTH2 and 12 nM for DP receptors.
MK 1903
T22986
MK 1903 is a potent and selective complete agonist for the hydroxy-carboxylic acid receptor 2 (HCA2). HCA2 is also known as G protein-coupled receptor 109A(GPR10...
Kuwanon H
TN1849
Kuwanon H, and possibly kuwanon G also, are specific antagonists for the gastrin-releasing peptide (GRP) -preferring receptor and can be useful for studying the ...
NF-56-EJ40
T12216
NF-56-EJ40 is an effective and highly selective antagonist of human SUCNR1 with an IC50 of 25 nM and a Ki of 33 nM.
Kisspeptin-10, human (TFA)(374675-21-5,FREE)
TP1345
Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor ...
GW-1100
T15448
GW-1100 is a selective GPR40 and FFAR1 antagonist for the study of diabetes and metabolic diseases.
GW9508
T1781
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
GPR120 Agonist 3
T15413
GPR120 Agonist 3 (GPR120-IN-1) is a selective agonist of Gpr120 ( logEC50: -7.62).
[Orn5]-URP acetate
TP1928L1
[Orn5]-URP acetate is an effective and selective Urotensin-II receptor (UT) antagonist (pEC50 = 7.24). [Orn5]-URP exhibits no agonist activity.
TUG-770
TQ0241
TUG-770 is a GPR40/FFA1 agonist with potential anti-inflammatory activity.TUG-770 can be used to study type 2 diabetes, dementia, and Alzheimer's disease.
2-Oleoylglycerol
T37526
2-Oleoylglycerol is a lipid found in palm kernel, sunflower seed and rice bran.2-Oleoylglycerol acts as a GPR119 agonist with neuroprotective effects and induces...
OX04528
T84313
OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research.
GPCR agonist-2
T60074
GPCR agonist-2 (4-(Cyclopropylamino)-3-nitrobenzoic acid) is an agonist of the orphan human GPCR GPR109B.
PU-WS13 hydrobromide
T5351L
PU-WS13 hydrobromide is a GRP94 inhibitor with anti-inflammatory activity and inhibits the proliferation of M2-like macrophages in mouse TNBC tumors.
CAY10786
T36036
CAY10786 (GPR52 antagonist-1) is an antagonist of G protein-coupled receptor 52 (GPR52, IC50 = 0.63 μM).
CAY10471 Racemate
T7359
CAY10471 Racemate (TM30089 Racemate) is a potent, highly selective CRTH2/DP 2 receptor antagonist. CAY10471 Racemate binds to the human CRTH2/DP2, DP1, and TP re...
Vincamine
T1286
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly...
DC260126
T7127
DC260126 is a small-molecule antagonist of FFA1 (GPR40)
SNAP 94847
T5406
SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces ...
Fasiglifam
T2351
Fasiglifam (TAK875) is a potent, selective and orally bioavailable GPR40 agonist.
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