PROTAC BRD4 Degrader 5

カタログ番号	製品名	別名	ターゲット
T36242	PROTAC BRD4 Degrader-5	PROTAC BRD4 Degrader-5	PROTACs
	PROTAC BRD4 Degrader-5 is a PROTAC-based BRD4 degrader. PROTAC BRD4 Degrader-5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines[1].		PROTACs
T31221L	DBRD9 HCl	dBRD9 HCl(2170679-45-3 Free base)	Epigenetic Reader Domain
	dBRD9 HCl is a PROTAC composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide . dBRD9 HCl is a potent and selective degrader of BRD9 (IC50 = 56.6 nM in MOLM-13 cells). dBRD9 HCl do...		Epigenetic Reader Domain
T18603	PROTAC BRD4 degrader for PAC-1		Others
	PROTAC BRD4 degrader for PAC-1 (compound 5) is a chimeric BET degrader GNE-987 conjugated with a disulfide-containing linker[1]. This PROTAC-linker conjugate specifically targets and degrades BRD4, enabling selective pro...		Others
T39985	(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2	(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2
	(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 is a synthetic E3 ligase ligand-linker conjugate comprised of a VHL ligand and a linker. It is utilized in PROTAC BRD4 Degrader-5 and PROTAC BRD4 Degrader-5-CO-PEG3-N3.
T17297	ZXH-3-26		Epigenetic Reader Domain , PROTACs
	ZXH-3-26 is a selective degrader of the PROTAC BRD4 (DC50/5h: ~ 5 nM).		Epigenetic Reader Domain , PROTACs
T36628	PROTAC BRD4 Degrader-8	PROTAC BRD4 Degrader-8	PROTACs
	PROTAC BRD4 Degrader-8 is a potent BRD4 inhibitor, with IC50s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells...		PROTACs

Compounds

PROTAC BRD4 Degrader-5

T36242

Synonym: PROTAC BRD4 Degrader-5

Target: PROTACs

dBRD9 HCl

T31221L

Synonym: dBRD9 HCl(2170679-45-3 Free base)

Target: Epigenetic Reader Domain

PROTAC BRD4 degrader for PAC-1

T18603

Synonym:

Target: Others

(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2

T39985

Synonym: (S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2

Target: Epigenetic Reader Domain, PROTACs

PROTAC BRD4 Degrader-8

T36628

Synonym: PROTAC BRD4 Degrader-8

Target: PROTACs

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-05308	CD45 Protein, Human, Recombinant (aa 1-529, His)	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPY-05387	SLAMF7 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPJ-00854	ETS1 Protein, Human, Recombinant (His)	Human	E. coli
	ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ...
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPY-05547	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPK-01363	SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01357	SIRP alpha V5 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...