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T17216 |
Valspodar
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PSC 833 |
P-gp
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Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer. |
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T7436 |
Cilofexor
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FXR
,
Autophagy
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Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist. |
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T12563 |
PrPSc-IN-1
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Others
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PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation(IC50 of 1.6 μM), with anti-prion activity. |
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T64334 |
Glycolithocholic acid, sodium salt
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Others
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Glycolithocholic acid sodium salt, the sodium form of Glycolithocholic acid, is a glycine-conjugated secondary bile acid utilized in diagnosing ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH), and primary s... |
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T76700 |
Simtuzumab
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GS 6624,AB 0024 |
Monoamine Oxidase
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Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensato... |
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T69724 |
Cilofexor tromethamine
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|
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Cilofexor, also known as GS-9674, is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilof... |
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T69517 |
Bexotegrast HCl
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|
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Bexotegrast, also known as PLN-74809, is a small-molecule, dual selective inhibitor of αVβ1 / αVβ6 for idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC). These integrins cause upstream activati... |
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T73155 |
BMS-986339
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BMS-986339 is an orally active, potent FXR agonist that interacts via H-bond formation with the His298 and ASN287 residues. It is utilized in research focused on primary biliary cirrhosis (PBC), primary sclerosing cholan... |
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T73237 |
GTPA2-OMe
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gTPA2-OMe is a potential hole transport layer candidate for perovskite solar cells (PSCs). |
