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Search Results for " SDMA "

ターゲット

Histone Methyltransferase

4

阻害剤

1

天然化合物

カタログ番号	製品名	別名	ターゲット
T9575	MRTX9768		Histone Methyltransferase
	MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.		Histone Methyltransferase
T40254	MRTX-1719		Histone Methyltransferase
	MRTX-1719 is a potent, first-in-class, selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.		Histone Methyltransferase
T36630	MRTX9768 hydrochloride
	MRTX9768 hydrochloride is a potent, orally active PRMT5 inhibitor. MRTX9768 hydrochloride is a synthetic lethal-based inhibitor binding the PRMT5-MTA complex[1]. MRTX9768 inhibits SDMA and cell proliferation in HCT116 MT...
TMIH-0361	N,N'-Dimethylarginine-d6
	N,N'-Dimethylarginine-d6 is a deuterated compound of N,N'-Dimethylarginine. N,N'-Dimethylarginine has a CAS number of 30344-00-4. SDMA is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher l...

Compounds

Target: Histone Methyltransferase

Target: Histone Methyltransferase

MRTX9768 hydrochloride

N,N'-Dimethylarginine-d6

カタログ番号	製品名	別名	ターゲット
T7344	SDMA	NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine	Endogenous Metabolite
	SDMA (Symmetric dimethylarginine) is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal disease (ESRD).		Endogenous Metabolite

天然物製品

Synonym: NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine

Target: Endogenous Metabolite

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