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T12242 |
Norvancomycin hydrochloride
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Desmethyl-vancomycin hydrochloride |
Antibacterial
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Norvancomycin hydrochloride (Desmethyl-vancomycin hydrochloride) is used as a treatment for endocarditis, osteomyelitis, pneumonia, sepsis, or soft tissue infections caused by Staphylococcus. |
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T70020 |
Vancomycin monohydrochloride
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Vancomycin monohydrochloride is an amphoteric glycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to peptidoglycan. |
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T70019 |
Tadalafil hydroxypiperidone
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Tadalafil hydroxypiperidone is an impurity of Tadalafil -- a phosphodiesterase 5-inhibitor used for the treatment of erectile dysfunction. |
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T40475 |
Ceftobiprole medocaril
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BAL5788 |
Antibacterial
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Ceftobiprole medocaril (BAL5788) is the parenteral prodrug of Ceftobiprole. Ceftobiprole is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA). |
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TQ0077 |
Ceftobiprole
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Ro 63-9141,BAL 9141 |
Antibacterial
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Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA; MIC90: 2 μg/mL). |
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T37740 |
N-Demethylvancomycin (hydrochloride)
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N-Demethylvancomycin is a glycopeptide antibiotic that has been found inNocardia orientalis.1It is active against several strains ofS. aureusandS. epidermidisin vitroandin vivo.2Formulations containing N-demethylvancomyc... |
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T16748 |
Ridinilazole
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SMT19969 |
Antibacterial
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Ridinilazole (SMT19969) is a novel narrow-spectrum nonabsorbable antibiotic. Ridinilazole showed potent inhibition of C. difficile (MIC90=0.125 mg/L) and was markedly more active than either metronidazole (MIC90 = 8 mg/L... |
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T4165 |
Delpazolid
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LCB01-0371 |
Antibacterial
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Antibiotic
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Delpazolid (LCB01-0371), also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomyc... |
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T23639 |
Adicillin
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NSC113137,NSC 113137,NSC-113137 |
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Adicillin is a penicillin antibiotic that works against vancomycin-resistant enterococci. |
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T29531 |
ABT-719 HCl
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A-816719.1,A 816719.1,ABT-719,ABT719,ABT 719,ABT-719 hydrochloride |
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ABT-719 is a 2-pyridinone antimicrobial agent that is more effective against Enterococcus faecalis strains than ciprofloxacin and vancomycin, which showed resistance to ciprofloxacin and vancomycin covering a range of MI... |
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T61799 |
Antibacterial agent 75
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Antibacterial agent 75 (compound 24) possesses antibacterial properties. Its notable attribute is the ability to re-sensitize VRSA (Vancomycin-Resistant Staphylococcus aureus) strains to vancomycin, as reported in refere... |
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T69176 |
YycG inhibitor 16
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YycG inhibitor 16 is a novel YycG inhibitor, inhibiting planktonic cells of E. faecalis, including the vancomycin- or linezolid-resistant strains. |
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T27964 |
Voxvoganan
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LTX109,Lytixar,LTX-109,LTX 109 |
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Lytixar is a Synthetic Antimicrobial Peptide, it shows activity against Daptomycin-Nonsusceptible, Methicillin-Resistant, Vancomycin-Intermediate, Vancomycin-Resistant, and Linezolid-Nonsusceptible Staphylococcus aureus.... |
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T38178 |
Ristocetin A (sulfate)
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Ristomycin III |
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Ristocetin A, a glycopeptide related to vancomycin, is an antibiotic produced by the microorganism Nocardia lurida[1].
Ristocetin A is currently in clinical use to treat bacterial infections [1]. Ristocetin A is an antib... |
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T32777 |
Lipid II binder 5107930
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Compound 5107930 |
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Lipid II binder 5107930 is a lipid II binder which causes specific upregulation of the vancomycin-resistance associated gene vraX, which is implicated in the cell wall stress stimulon that confers glycopeptide resistance... |
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T37263 |
14-methyl Pentadecanoic Acid methyl ester
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14-methyl Pentadecanoic acid methyl ester is a methylated fatty acid methyl ester that has been found in S. zeai sea sponges as the fatty acyl component of zeamide, A. indica leaf extract, and C. vulgaris and H. pluviali... |
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TP2286 |
Quinupristin (mesylate) (120138-50-3 free base)
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Quinupristin (mesylate) |
Others
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Quinupristin is a streptogramin antibiotic. Streptogramins, a class of antibiotics, is effective in the treatment of vancomycin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus, which are two of the ... |
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T38125 |
Platencin
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Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis, which is also the source of platensimycin . Platencin inhibits two key enzymes in bacterial fatty acid synthesis, β-ketoacyl-ACP... |
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T1747L |
Tedizolid phosphate disodium salt
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Torezolid phosphate sodium salt,DA 7218,TR-701,TR 701 |
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Tedizolid phosphate is a novel antibacterial prodrug. Tedizolid phosphate is a next-generation oxazolidinone with activity against both methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus sp... |
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T80193 |
Enterocin Hybrid 1
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K1-EJ hybrid |
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Enterocin Hybrid 1, an antibacterial agent, effectively inhibits Vancomycin-resistant Enterococcus faecium and Staphylococcus haemolyticus [1]. |
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T36706 |
Bottromycin A2
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Bottromycin A2is an antibiotic originally isolated fromStreptomyces.1It blocks the binding of aminoacyl-tRNA to the A site of the 50S ribosome, inhibiting protein synthesis.2Bottromycin A2is active against clinical isola... |
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T76990 |
Suvratoxumab
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Suvratoxumab (MEDI4893) is a high-affinity, long-acting humanized IgG1κ anti-α-toxin monoclonal antibody. It effectively neutralizes α-toxin, a principal virulence factor of S. aureus, enhancing survival and diminishing ... |
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T36892 |
4'-Acetyl Chrysomycin A
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4'-Acetyl chrysomycin A is a bacterial metabolite and derivative of chrysomycin A that has been found inStreptomycesand has antibacterial and anticancer activities.1It is active against strains of methicillin-resistantS.... |
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T38009 |
Kocurin
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Kocurin is a thiazolyl peptide originally isolated fromK. palustrisand has antibiotic activity.1It is active against methicillin-resistantS. aureus(MRSA; MIC = 0.25 μg/ml), as well asB. subtilisandE. faeciumin a solid ag... |
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T80192 |
Enterocin K1
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EntK1 |
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Enterocin K1 (EntK1) is a ribosomally synthesized bacteriocin that exerts potent antibacterial activity against Vancomycin-resistant Enterococcus (VRE). It targets Enterococcus faecalis by interacting with the Eep protei... |
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T37465 |
CAY10742
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CAY10742 is an orally bioavailable oxadiazole antibiotic.1It is active against the Gram-positive bacteriaS. aureus,S. epidermidis,S. haemolyticus,B. cereus,B. licheniformis,E. faecalis, andE. faecium(MICs = 1-4 μg/ml), i... |
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T72141 |
Ceftobiprole medocaril sodium
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BAL5788 sodium |
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Ceftobiprole medocaril sodium (BAL5788) is a parenteral prodrug of Ceftobiprole, a pyrrolidinone cephalosporin administered intravenously. As a broad-spectrum cephalosporin, Ceftobiprole exhibits high in vitro activity a... |
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T74269 |
Antibacterial agent 83
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Antibacterial agent 83 (compound 17h) exhibits strong antibacterial efficacy against diverse strains of vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA), significant... |
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T37006 |
Previridicatumtoxin
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Previridicatumtoxin is a fungal metabolite that has been found inP. aethiopicumand has diverse biological activities.1,2It is an intermediate in the biosynthesis of the mycotoxin viridicatumtoxin . Previridicatumtoxin is... |
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T35437 |
(-)-Viriditoxin
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(-)-Viriditoxin is a mycotoxin originally isolated from A. viridinutans that has antibacterial and antiproliferative activity. It is active against methicillin-sensitive and -resistant S. aureus (MSSA and MRSA, respectiv... |
