Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA; MIC90: 2 μg/mL).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 34,000 | |||
5 mg | 在庫あり | ¥ 85,500 | |||
10 mg | 在庫あり | ¥ 128,000 | |||
25 mg | 在庫あり | ¥ 206,000 | |||
50 mg | 在庫あり | ¥ 280,000 | |||
100 mg | 在庫あり | ¥ 379,000 |
説明 | Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA; MIC90: 2 μg/mL). |
ターゲット&IC50 | MRSA:2 μg/mL (MIC90) |
In vitro | Ceftobiprole has demonstrated activity against important gram-positive bacteria, including penicillin-resistant S. pneumonia (PRSP), Methicillin-resistant S. aureus (MRSA), and E. faecalis (MIC90 values of 0.25, 2, and 2 mcg/mL). Ceftobiprole has also demonstrated potent in vitro activity against several clinical isolates of community-associated Methicillin-resistant S. aureus (CA-MRSA), vancomycin-intermediate S. aureus (VISA), and Vancomycin-resistant S. aureus (VRSA), with a minimum inhibitory concentration (MIC) of 2 mcg/mL [1]. Ceftobiprole is highly active against S. aureus, with MICs ranging from 0.12 to 4 mg/L (only one resistant strain, MIC of 4 mg/L). Furthermore, Ceftobiprole is twice more active on Methicillin-susceptible S. aureus (MSSA) strains with MIC50 and MIC90 of 0.5 mg/L than on MRSA strains with MIC50 and MIC90 of 1 mg/L. Moreover, Panton-Valentine leukocidin (PVL)+MRSA is slightly more susceptible to Ceftobiprole (MIC50: 0.5 mg/L, MIC90: 1 mg/L) than PVL-MRSA (MIC50 and MIC90 of 1 mg/L) [2]. |
別名 | Ro 63-9141, BAL 9141 |
分子量 | 534.57 |
分子式 | C20H22N8O6S2 |
CAS No. | 209467-52-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: < 1mg/ml (insoluble), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Ceftobiprole 209467-52-7 Microbiology/Virology Antibacterial cephalosporin BAL9141 inhibit vancomycin penicillin staphylococci Ro 63-9141 Bacterial pyrrolidinone BAL-9141 pathogens gram-positive BAL 9141 VRSA gram-negative Inhibitor MRSA methicillin inhibitor