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T14141 |
AGI-24512
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DNA
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AGI-24512 is a potent inhibitor of methionine adenylyltransferase 2α (MAT2A) (IC50: 8 nM).AGI-24512 shows antiproliferative activity in MTAP-deficient cancer cells.AGI-24512 inhibits MAT2A, which causes DNA damage in MTA... |
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T11950 |
MAT2A inhibitor 2
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Others
,
Methionine Adenosyltransferase (MAT)
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MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A). |
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T5191 |
PF-9366
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Others
,
Methionine Adenosyltransferase (MAT)
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PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM). |
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T9262 |
MAT2A inhibitor 4
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Others
,
Methionine Adenosyltransferase (MAT)
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MAT2A inhibitor 4 is an inhibitor of the catalytic subunit of methionine S-adenosyltransferase-2, which is used in cancer research. |
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T11285 |
FIDAS-5
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Others
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FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities. |
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T11284 |
FIDAS-3
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Others
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Wnt/beta-catenin
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Methionine Adenosyltransferase (MAT)
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FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for ... |
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T79349 |
MAT2A-IN-11
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Methionine Adenosyltransferase (MAT)
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MAT2A Allosteric Inhibitor 1, also known as Compound 5, is a selective inhibitor of methionine adenosyltransferase (MAT) demonstrating potent activity with an IC50 value of 6.8 nM [1]. |
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T16013 |
MAT2A inhibitor 1
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Others
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MAT2A inhibitor 1 is an inhibitor of methionine adenosyltransferase 2A (MATA2) (IC50 < l00 nM). |
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T60668 |
MAT2A inhibitor 3
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Others
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MAT2A inhibitor 3 can be used in the cancer research. MAT2A inhibitor 3 is a inhibitor of methionine adenosyltransferase 2A (MAT2A) with an IC 50 of <200 nM [1]. |
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T60903 |
MAT2A-IN-4
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Others
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MAT2A-IN-4 can be used for the cancer research that is an inhibitor of methionine adenosyltransferase 2A (MAT2A)[1]. |
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T10259 |
AGI-25696
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Others
,
Methionine Adenosyltransferase (MAT)
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AGI-25696 is an inhibitor of methionine adenosyltransferase 2A (MATA2). AGI-25696 blocks the growth of MTAP-deleted tumors in vivo and can be used for studies about the treatment of cancer. |
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T9730 |
AGI-41998
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Others
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AGI-41998 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A) that penetrates the blood-brain barrier.AGI-41998 inhibits s-adenosylmethionine (SAM) metabolizing enzymes and methionine adenosyltransferase 2... |
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T31200 |
Dansylmethionine
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Dansyl methionine,Dansyl-met |
Others
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Dansylmethionine is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM-e is produced and consumed in the... |
