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Search Results for " fibrillogenesis "

ターゲット

3

阻害剤

2

天然化合物

7

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T0382 Eprodisate disodium NC-503 Others
Eprodisate disodium (NC-503) is a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.
T80104 Z-Phe-Ala-diazomethylketone PADK
Z-Phe-Ala-diazomethylketone directly binds to Aβ42 monomers and small oligomers, effectively inhibiting the formation of Aβ42 dodecamers and preventing Aβ42 fibrillogenesis in solution. This compound holds potential for ...
T11207 Entacapone sodium salt Others
Entacapone sodium salt inhibits catechol-O-methyltransferase(COMT) with similar IC50 in different tissues including live, duodenum, kidney and lung, but entacapone is more active than tolcapone in those tissues. Entacapo...
カタログ番号 製品名 別名 ターゲット
T1686 Hematoxylin Hydroxybrazilin,Natural Black 1,Haematoxylin Beta Amyloid , Others
Hematoxylin (Natural Black 1) is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink.
TN1216 2-O-Acetyl-20-hydroxyecdysone 20-Hydroxyeedysone 2-acetate Beta Amyloid , Others
2-O-Acetyl-20-hydroxyecdysone is an ecdysone present in insects and terrestrial plants. 2-O-Acetyl-20-hydroxyecdysone inhibits amyloid-β42-induced cytotoxicity and is able to reduce the formation of Aβ oligomers by promo...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His) Human HEK293
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-01613 Periostin/OSF-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPH-02494 AEBP1 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix.; May positively regulate MAP-kinase activity in adipocytes, leading to enhanced...
TMPH-01338 Fibronectin Protein, Human, Recombinant (His) Human E. coli
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell s...
TMPJ-00924 Decorin Protein, Mouse, Recombinant (His) Mouse Human Cells
Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a gua...
TMPJ-01005 Lumican Protein, Mouse, Recombinant (His) Mouse Human Cells
Keratan sulfate proteoglycan lumican, mostly known as lumican, belongs to the SLRP class II subfamily and the small leucine-rich proteoglycan (SLRP) family. Lumican binds to laminin. It has positive regulation of transcr...
TMPH-03114 ITGB1 Protein, Pig, Recombinant (His & Myc) Sus scrofa (Pig) E. coli
Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. I...