Beta Amyloid

Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms. It is now believed that certain misfolded oligomers (known as "seeds") can induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection.

Cat. No.	製品名	CAS No.	Purity
T7566L1	GRGDSPK acetate	144027-77-0	98%
T7566L1	GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.
T1637	Deferoxamine Mesylate	138-14-7	98%
T1637	Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also is an inhibitor of ferroptosis.
T22204	LY 2389575 hydrochloride	885104-09-6	98%
T22204	LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochlor...
T35941	DC-Chol hydrochloride	166023-21-8	98%
T35941	DC-Chol hydrochloride(DC-Cholesterol hydrochloride) inhibited the formation of Aβ40 fibrils under appropriate experimental conditions and significantly inhibited...
T22932L	LPYFD-NH2 acetate		98%
T22932L	LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).
T6708	Tolcapone	134308-13-7	98%
T6708	Tolcapone is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopa and carbidopa.
T7680	GSNKGAIIGLM(131602-53-4(free base))	T7680	98%
T7680	GSNKGAIIGLM is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide.
T2873	Ginsenoside Rg2	52286-74-5	98%
T2873	Ginsenoside Rg2 is one of the major active components of ginseng, act as an NF-κB inhibitor.
TQ0026	MDR-1339	1018946-38-7	98%
TQ0026	MDR-1339 (DWK-1339) is an orally active and blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.
TP1935L1	RAGE antagonist peptide acetate	TP1935L1	98%
TP1935L1	RAGE antagonist peptide acetate is an advanced antagonist of glycation end products (RAGE). RAGE antagonist peptide acetate possesses anti-tumor and anti-inflamm...
T11043	Dihydroergocristine mesylate	24730-10-7	98%
T11043	Dihydroergocristine mesylate(DHEC mesylate) is the methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of men...
T14673	BMS 299897	290315-45-6	98%
T14673	BMS 299897 is a sulfonamide γ-secretase inhibitor. It has an IC50 of 7 nM for Aβ production inhibition in HEK293 cells stably overexpressing amyloid precursor pr...
T5810	TABERSONINE HYDROCHLORIDE	29479-00-3	98%
T5810	TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1 42) aggregation and toxicity.
T3402	20(S)-Ginsenoside Rg3	14197-60-5	98%
T3402	Ginsenoside Rg3 possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the prol...
T7905	PBD-150	790663-33-1	98%
T7905	PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)
T14284	β-Amyloid (25-35)	131602-53-4	98%
T14284	Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.
T7562	β-Amyloid (31-35)	149385-65-9	98%
T7562	β-Amyloid 31-35(TFA) is the shortest sequence of native Amyloid-β peptide.
TP1866L	β-amyloid 1-11 acetate(190436-05-6 free base)	TP1866L	98%
TP1866L	β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
T0795	Rutin	153-18-4	98%
T0795	Rutin, a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
TP1359L	Amyloid β Peptide (42-1)(human) acetate		98%
TP1359L	Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42). Amyloid β Peptide (42-1)(human) acetate is a 42-amino acid peptide whic...