|
T78562 |
FX-06
|
Fibrin-derived peptide Bβ15-42 |
|
|
FX-06 (Fibrin-derived peptide Bβ15-42) is a peptide derived from the fibrin Bbeta chain. It interacts with VE-cadherin to inhibit leukocyte transmigration and initiate VE-cadherin-mediated signaling pathways. This compou... |
|
T4502 |
BISMUTH SUBGALLATE
|
Dermatol Puder,Bismuth Gallate |
Others
|
|
Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema. |
|
T19786 |
Hematin
|
Ferrihemate,Ferriheme hydroxide,Ferriheme,Ferrihemic acid |
Others
|
|
Hematin (Ferrihemic acid) is an iron-containing porphyrin. It is used for testing in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
|
TP1060 |
GPRP acetate (67869-62-9 free base)
|
Pefabloc FG,Pefa 6003,GPRP acetate |
Others
|
|
GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex (GPIIbIIIa). |
|
TP1143L |
Fibrinopeptide A, human acetate
|
Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate |
Others
|
|
Fibrinopeptide A, human acetate (Human fibrinopeptide A acetate) is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A (FPA) is produced from the N-terminal Aα region of fibrinogen prote... |
|
TP1736L |
Fibrinogen-Binding Peptide fb-acetate
|
Fibrinogen-Binding Peptide （137235-80-4 fb-acetate) |
Others
|
|
Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits ... |
|
TP1163 |
Fibrinopeptide B, human
|
FPB,human |
|
|
Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer. |
|
T78367 |
Fibrinogen (Bovine)
|
|
|
|
Fibrinogen (Bovine) is a molecule selectively proteolyzed, assembling into a fibrin clot upon thrombin activation [1]. |
|
TP1736 |
Fibrinogen-Binding Peptide
|
|
|
|
Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen, a soluble plasma protein, is a cofactor in pl... |
|
TP1142 |
Fibrinopeptide A, human TFA
|
Human fibrinopeptide A TFA |
|
|
Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain.The conversion of monomeric fibrinogen into polymeric fibr... |
|
T80682 |
γ-Fibrinogen 377-395 TFA
|
|
|
|
γ-Fibrinogen377-395 TFA is an inhibitory peptide derived from fibrinogen, which also functions as a fibrinogen epitope. It effectively blocks microglial activation and impedes fibrin-Mac-1 interactions in vitro. Addition... |
|
T80683 |
γ-Fibrinogen 377-395
|
|
|
|
γ-Fibrinogen377-395 is a peptide derived from fibrinogen, functioning both as an inhibitory molecule and an epitope. It inhibits microglial activation, disrupts fibrin-Mac-1 interactions in vitro, and mitigates experimen... |
|
TP1143 |
Fibrinopeptide A, human
|
Human fibrinopeptide A |
|
|
Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A (FPA) is produced from the N-terminal Aα region of fibrinogen protein, on cleavage by thrombin. |
|
TP1864 |
[Glu1]-Fibrinopeptide B
|
|
|
|
[Glu1]-Fibrinopeptide B, a derivative of fibrinopeptide B amino acid residues 1-14, originates from human fibrinopeptide B (hFpB). hFpB is a proteolytic cleavage product of the fibrinogen B beta-chain, specifically gener... |
|
TP1162 |
Fibrinopeptide B, human TFA (36204-23-6 free base)
|
FPB,human TFA,Fibrinopeptide B, human TFA |
|
|
FibrinopeptideB,human is a 14-amino acid polypeptide released from the amino terminus of the fibrinogen segment. |
|
TP1778 |
Fibrinogen Binding Inhibitor Peptide
|
|
|
|
Fibrinogen Binding Inhibitor Peptide, a synthetic dodecapeptide, represents the specific platelet receptor recognition site of the human fibrinogen g-chain (residues 400-411). |
|
T1736 |
Apixaban
|
BMS-562247-01 |
Factor Xa
|
|
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and pr... |
|
T1184 |
Rivaroxaban
|
BAY 59-7939 |
Factor Xa
,
Thrombin
|
|
Rivaroxaban (BAY 59-7939) is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both ... |
|
T78215 |
Dechloro Rivaroxaban
|
|
Factor Xa
,
Others
|
|
Dechloro Rivaroxaban is an orally active and highly selective Factor Xa inhibitor.Dechloro Rivaroxaban has a significant inhibitory effect on free FXa in humans.Dechloro Rivaroxaban also has an inhibitory effect on throm... |
|
T38736 |
Nattokinase
|
|
|
|
Nattokinase is a powerful fibrinolytic enzyme that effectively hydrolyzes fibrin and plasmin substrate, leading to the breakdown of blood clots. Its efficacy renders it valuable for cardiovascular disease studies. |
|
T82201 |
H-Gly-Pro-Arg-Pro-NH2
|
|
|
|
H-Gly-Pro-Arg-Pro-NH2 is a tetrapeptide that replicates the N-terminal Gly-Pro-Arg sequence in the alpha (α) chain of fibrin and inhibits its polymerization [1]. |
|
T26657 |
AR-H067637
|
|
|
|
AR-H067637 is a rapid-binding, reversible and potent (inhibition constant K(i) = 2-4 nM), competitive inhibitor of thrombin, as well as of thrombin bound to fibrin (clot-bound thrombin) or to thrombomodulin. The total am... |
|
TP1555 |
Fibronectin Active Fragment Control
|
|
|
|
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix ... |
|
T35583 |
Hirudin (54-65; non-sulfated) (trifluoroacetate salt)
|
|
|
|
Hirudin (54-65; non-sulfated) is a desulfated peptide fragment of hirudin, an anticoagulant produced byH. medicinalis.1It inhibits fibrin clot formation induced by isolated bovine thrombin with an IC50value of 3.7 μM.2
1... |
|
T62961 |
ZK824859 hydrochloride
|
|
|
|
ZK824859 hydrochloride is a selective, orally active inhibitor of urokinase-type fibrinogen activator (uPA) with IC50 values of 79 nM, 1580 nM and 1330 nM for human uPA, tPA and fibrin, respectively. |
|
T25976 |
Ppack HCl
|
Ppack dihydrochloride,Fprmecl, dihydrochloride |
|
|
Ppack HCl is a peptide derivative that irreversibly and specifically suppresses thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki: 0.24 nM). It has been utilized as an... |
|
T25977 |
Ppack trifluoroacetate
|
Ppack trifluoroacetate salt |
|
|
Ppack trifluoroacetate is a peptide derivative that irreversibly and specifically suppresses thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki: 0.24 nM). It has been u... |
|
T82286 |
Glycylglycylcysteine
|
|
|
|
Glycylglycylcysteine is an inhibitor of Thrombin Activatable Fibrinolysis Inhibitor (TAFI), exhibiting a K_i value of 0.99 µM and an IC_50 of 9.4 µM in TAFI substrate assays. TAFI, a basic carboxypeptidase, hinders fibri... |
|
T80119 |
Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)
|
|
Thrombin
|
|
Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide with greater thrombin affinity than Hirugen, exhibiting a dissociation constant (K D) of less than 100 nM. This compound acts as an antithromb... |
|
TP2234 |
Coagulation factor II (thrombin) B chain fragment [Homo sapiens]
|
|
Others
|
|
Thrombin is a "trypsin-like" serine protease that is encoded by the F2 gene in humans. Thrombin is produced by the enzymatic cleavage of two sites on prothrombin by activated Factor X (Xa). Thrombin in turn acts as a ser... |
|
T62846 |
Freselestat quarterhydrate
|
|
|
|
Freselestat quarterhydrate (ONO-6818 quarterhydrate) is a potent, orally active inhibitor of neutrophil elastase (Ki: 12.2 nM). quarterhydrate is more than 100-fold less active than other proteases such as trypsin, prote... |
|
T78018 |
Plasminogen
|
|
|
|
Plasminogen is a zymogen secreted as a precursor protein that, when cleaved by urokinase plasminogen activator (uPA) or tissue plasminogen activator (tPA), is converted into plasmin. Plasmin is a protease with broad spec... |
|
T83663 |
Mn(III) Protoporphyrin IX Chloride
|
Manganese(III) Protoporphyrin IX Chloride |
|
|
Mn(III) protoporphyrin IX chloride is a metalloporphyrin that, at a concentration of 10 µM, promotes mRNA expression of δ-aminolevulinate synthase and heme oxygenase (HO) in chick embryo liver cells, enzymes crucial for ... |
|
T36225 |
N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)
|
|
|
|
N-p-Tosyl-Gly-Pro-Lys-pNA is a colorimetric substrate for plasmin.1,2,3Plasmin binds and hydrolyzes N-p-tosyl-Gly-Pro-Lys-pNA to releasep-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as... |
