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Factor Xa

Factor X, also known by the eponym Stuart–Prower factor, is an enzyme  of the coagulation cascade. It is a serine endopeptidase (protease group S1, PA clan). Factor X is synthesized in the liver and requires vitamin K for its synthesis.Factor X is activated, by hydrolysis, into factor Xa by both factor IX (with its cofactor, factor VIII in a complex known as intrinsic Tenase) and factor VII with its cofactor, tissue factor (a complex known as extrinsic Tenase ). It is therefore the first member of the final common pathway or thrombin pathway.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T4690 Betrixaban hydrochloride(330942-05-7(free base)) T4690 98%
Betrixaban is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM).
T2368L Edoxaban 480449-70-5 98%
Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K i s of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respecti...
T0642 2-Methoxyphenothiazine 1771-18-2 98%
2-Methoxy Phenothiazine is light yellow or light gray solid.
T1184 Rivaroxaban 366789-02-8 98%
Rivaroxaban is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administr...
T1736 Apixaban 503612-47-3 98%
Apixaban is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the c...
T39463 Asundexian 2064121-65-7 98%
Asundexian is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiti...
T66256 Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 503614-91-3 98%
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagula...
T2368 Edoxaban Tosylate Monohydrate 1229194-11-9 98%
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.
T4076 Fondaparinux sodium 114870-03-0 98%
Fondaparinux Sodium is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
T6531 Heparin sodium salt 9041-08-1 98%
Heparin sodium is a sulfated polysaccharide, which belongs to the family of glycosaminoglycans. It is utilized as an anticoagulant and interacted with diverse p...
T10174 5-R-Rivaroxaban 865479-71-6 98%
5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor (IC50 0.7 nM; Ki 0...
T20454 4-Chlorophenylurea 140-38-5 98%
4-Chlorophenylurea is a novel orally bioavailable inhibitor of factor Xa.
T4980 Betrixaban maleate 936539-80-9 98%
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among ...
T31206 Darexaban 365462-23-3 98%
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothr...
T4341 Betrixaban 330942-05-7 98%
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among ...
T27318 Fidexaban 183305-24-0 98%
Fidexaban is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays
T67853 Rivaroxaban Impurity 1151893-81-0 98%
Rivaroxaban Impurity is a potent Blood-coagulation factor Xa inhibitor, IC50= 66 nM.
T0372 Gabexate mesylate 56974-61-9 98%
Gabexate mesylate is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a ...
T0775 Coumarin 91-64-5 98%
Coumarin is a chemical compound/poison found in many plants, notably in high concentration in the tonka bean, woodruff, and bison grass. It has clinical value as...
T19488 O-Desmethyl apixaban sulfate sodium T19488 98%
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.
Betrixaban hydrochloride(330942-05-7(free base))
T4690
Betrixaban is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM).
Edoxaban
T2368L
Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K i s of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respecti...
2-Methoxyphenothiazine
T0642
2-Methoxy Phenothiazine is light yellow or light gray solid.
Rivaroxaban
T1184
Rivaroxaban is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administr...
Apixaban
T1736
Apixaban is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the c...
Asundexian
T39463
Asundexian is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiti...
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
T66256
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagula...
Edoxaban Tosylate Monohydrate
T2368
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.
Fondaparinux sodium
T4076
Fondaparinux Sodium is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
Heparin sodium salt
T6531
Heparin sodium is a sulfated polysaccharide, which belongs to the family of glycosaminoglycans. It is utilized as an anticoagulant and interacted with diverse p...
5-R-Rivaroxaban
T10174
5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor (IC50 0.7 nM; Ki 0...
4-Chlorophenylurea
T20454
4-Chlorophenylurea is a novel orally bioavailable inhibitor of factor Xa.
Betrixaban maleate
T4980
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among ...
Darexaban
T31206
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothr...
Betrixaban
T4341
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among ...
Fidexaban
T27318
Fidexaban is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays
Rivaroxaban Impurity
T67853
Rivaroxaban Impurity is a potent Blood-coagulation factor Xa inhibitor, IC50= 66 nM.
Gabexate mesylate
T0372
Gabexate mesylate is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a ...
Coumarin
T0775
Coumarin is a chemical compound/poison found in many plants, notably in high concentration in the tonka bean, woodruff, and bison grass. It has clinical value as...
O-Desmethyl apixaban sulfate sodium
T19488
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.
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