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T24533 |
Nicotinoyl azide
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N-Az,NAz,N Az |
Others
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Nicotinoyl azide (N-Az) is a probe of light-activated chemical. It has been used to measure the solvent accessibility of purine nucleobases. |
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T19060 |
SPQ
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Others
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SPQ is used to measure membrane chloride transport mechanisms. |
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T5039 |
Aminohippurate sodium
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Sodium 4-aminohippurate Hydrate,Sodium p-aminohippurate,p-Aminohippuric acid sodium salt |
Others
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Aminohippurate sodium (Sodium p-aminohippurate) is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. |
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T19028 |
Monochlorobimane
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mBBr,Chlorobimane |
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Monochlorobimane (mBBr) is a fluorescent dye with a λex value of 380 nm and a λem value of 470 nm.Monochlorobimane can be used to measure glutathione (GSH) in cells. |
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T36951 |
N-(p-Tosyl)-GPR-pNA acetate
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Others
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N-(p-Tosyl)-GPR-pNA acetate is a colorimetric substrate for thrombin that can act as a measure of thrombin activity. |
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T14577 |
Biotin-DADOO
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EZ-Link Amine-PEO2-Biotin,Biotinyl-3,6-dioxaoctanediamine |
Others
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Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine) is a biotinylation reagent that can be used to synthesize a biotin-estradiol conjugate(i.e., biotin-DADOO-estradiol) to develop a direct, broad-range enzyme immunoassay to m... |
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T14057 |
6-CFDA
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6-Carboxyfluorescein diacetate |
Others
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6-CFDA (6-Carboxyfluorescein diacetate) is fluorescent polyanionic probe that used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption. |
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T37034 |
H-Gly-Arg-pNA dihydrochloride
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H-Gly-Arg-Pna 2HCl |
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H-Gly-Arg-pNA dihydrochloride (H-Gly-Arg-Pna 2HCl) belongs to the class of peptides that bind to 1,2 thrombin and can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity. |
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T50000 |
2-Iodohippuric Acid
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Others
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2-Iodohippuric Acid can be used to measure renal clearance for renal function studies, and for the diagnosis of certain diseases, such as liver and kidney disease. In addition, it is used in the synthesis of certain drug... |
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TP1789L |
Malantide acetate(86555-35-3 free base)
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PKA
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PKC
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Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activ... |
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T15609 |
JC-1
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CBIC2 |
Others
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JC-1 (CBIC2) is a fluorescent lipophilic carbocyanine dye. It has been used to measure mitochondrial membrane potential. JC 1 can be used in a probe for measuring mitochondrial membrane potential by flow cytometry. |
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T26360 |
Benperidol
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R4584,R-4584,Anquil,McN-JR-4584,R 4584 |
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Benperidol (Anquil) is a butanone analog with antipsychotic and stabilizing properties, and has been shown to be effective in blocking D2 receptors.Benperidol can be used in positron emission tomography (PET) scanning to... |
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T39518 |
PFB-FDGlu
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Others
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PFB-FDGlu is a lysosomal Glucocerebrosidase (GCase) substrate with cell-permeable specificity that is cleaved to produce fluorescein.PFB-FDGlu is often used in conjunction with a flow cytometer to measure GCase activity ... |
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T11093 |
DPPH
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2,2-Diphenyl-1-picrylhydrazyl |
Others
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DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a cell-permeable, stable free radical that is commonly used to evaluate the ability of compounds to act as free radical scavengers or hydrogen donors and to measure the antioxidant... |
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T30444L |
Bicisate (Free base)
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Bicisate |
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Bicisate is usually complex with technetium Tc99m for its usage as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). |
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T19150 |
5-BrUTP sodium salt
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5-Bromouridine 5'-triphosphate sodium salt |
Others
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5-BrUTP sodium salt can be used to label RNA to measure the transcription. |
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T69443 |
Aminobutane bisphosphonate
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Aminobutane bisphosphonate is a powerful inhibitor of bone resorption. It can potentially be a useful measure for controlling hypercalcemia in patients with carcinoma. |
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T30444 |
Bicisate dihydrochloride
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Bicisate HCl |
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Bicisate dihydrochloride is usually complex with technetium Tc99m to measure cerebral blood flow with single-photon emission computed tomography (SPECT). |
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T35141 |
WW-781
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WW 781,NK 2935 |
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WW-781 is used to measure action potential propagation in the heart. |
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T35926 |
Bz-IEGR-pNA (acetate)
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Bz-IEGR-pNA is a colorimetric substrate for Factor Xa.1 Factor Xa preferentially binds to and cleaves the Ile-Glu-Gly-Arg (IEGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric d... |
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T33955 |
PF-6808472
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OX-44,OX44,PF 6808472,OX 44,PF6808472 |
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PF-6808472 is a cell permeable covalent probe suitable for click chemistry designated to measure kinase selectivity in intact cells. PF-6808472 contains sulfonyl fluoride group, which react with conserved lysine residue ... |
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T39672 |
Ac-Ile-Glu-Thr-Asp-pNA
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Ac-Ile-Glu-Thr-Asp-pNA is a caspase-8 substrate that undergoes enzymatic binding and cleavage specifically at the Ile-Glu-Thr-Asp (IETD) peptide sequence. This cleavage results in the release of p-nitroalinide, which can... |
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T19873 |
Edoxaban M4
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D21-2393,D21 2393,UNII-IV344R972X,Edoxaban 4-Carboxylic Acid |
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D21-2393 subjects received a single-oral-dose of edoxaban 30-90 mg in each study occasion under fasting condition. Serial blood samples were collected to measure the plasma concentrations of edoxaban and its major active... |
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T37834 |
G3-CNP
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G3-CNP is a colorimetric substrate for α-amylases.1Upon hydrolysis by α-amylases, 2-chloro-4-nitrophenol is released which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity. G3-CNP has... |
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T76512 |
Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2
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Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 is a peptide substrate specific to HIV-1 protease, serving as the variable component in peptidolytic assays designed to measure the enzyme's inhibition [1] [2]. |
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T37434 |
P-Nitrophenylphosphorylcholine
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p-Nitrophenylphosphorylcholine is a chromogenic substrate that is used to measure phospholipase C (PLC) activity. Hydrolysis of p-nitrophenylphosphorylcholine by PLC results in the liberation of p-nitrophenol, which can ... |
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T37583 |
XTT (sodium salt hydrate)
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XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator.1,2It is frequently used in colorime... |
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T36225 |
N-p-Tosyl-Gly-Pro-Lys-pNA (acetate)
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N-p-Tosyl-Gly-Pro-Lys-pNA is a colorimetric substrate for plasmin.1,2,3Plasmin binds and hydrolyzes N-p-tosyl-Gly-Pro-Lys-pNA to releasep-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as... |
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TP1789 |
Malantide
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Malantide is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in v... |
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T76383 |
Casein Kinase II Receptor Peptide
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Casein Kinase II Receptor Peptide, a substrate for casein kinase II, exhibits a Km value of 500 µM. It is utilized to measure the activity of casein kinase II in crude enzyme preparations [1]. |
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T81838 |
Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human)
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Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a peptide utilized as a fluorescence resonance energy transfer (FRET) based substrate for proteolytic activity assays, wherein the cleavage-induced change in f... |
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T76091 |
Ac-WEHD-AFC TFA
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Ac-WEHD-AFC TFA is a fluorogenic substrate for caspase-1, used to measure the enzyme's activity in researching tumors and inflammation [1]. |
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T30078 |
ANNINE-6plus
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ANNINE-6plus is a water soluble voltage sensitive dye (also called potentiometric dyes). This compound was developed at the Max Planck Institute for Biochemistry in Germany. It is used to optically measure the changes in... |
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T76610 |
Hippuryl-His-Leu-OH
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Hippuryl-His-Leu-OH serves as a substrate to measure angiotensin I converting enzyme activity. Upon its cleavage, the resultant His-Leu moiety reacts with o-phthaldialdehyde or Fluorescamine, facilitating fluorescence de... |
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T38123 |
5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
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5(6)-Carboxy-2’,7’-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting c... |
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T83800 |
6-Biotin-17-NAD+ sodium
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6-Biotin-17-Nicotinamide adenine dinucleotide,β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide |
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6-Biotin-17-NAD+, a biotinylated derivative of the signaling molecule and enzyme cofactor NAD+, is utilized in high-throughput screening (HTS) assays to measure the activity of mitochondrial complex I, also referred to a... |
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T35957 |
PBD-BODIPY
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PBD-BODIPY is a probe for the spectrophotometric measurement of autoxidation reactions. Co-autoxidation of the PBD-BODIPY signal carrier and a hydrocarbon co-substrate can be quantified by monitoring loss of absorbance a... |
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T37797 |
Coumarin-Quinone Conjugate
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Coumarin-quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases.1It is comprised of a coumarin fluorophore conjugated to a ubiquinone analog that can be reduced by NADH:ubiquinone oxidoreductase... |
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T18922 |
BCECF
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2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein |
Others
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BCECF is a fluorescent probe commonly used to measure pH. It is a dual-excitation ratiometric pH indicator with a pKa of ~6.98. Measurements of pH are made by determining the ratio of emission intensity, detected at 535 ... |
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T37217 |
N-Decanoyl p-Nitroaniline
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N-Decanoyl p-nitroaniline (DepNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity. FAAH is a relatively unselective enzyme in that it accepts a var... |
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T70896 |
PF05020182
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PF05020182 is novel potent and selective Kv7.2/4 potassium channel opener. PF-05020182 (2) significantly inhibits convulsions in the MES assay at doses tested, consistent with in vitro activity measure. The physiochemic... |
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T73604 |
Methyl Green zinc chloride
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Methyl Green Zinc Chloride, a potent fluorescent dye, is utilized for staining DNA in cells and electrophoretic gels. It serves as a direct measure of viability through microscopy and flow cytometry, exhibiting peaks at ... |
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T37244 |
Palmitoyl thio-PC
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Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Palmitoyl thio-PC is a chromogenic PLA2 substrat... |
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T36385 |
Ansatrienin A
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Ansatrienin A is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis. In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 64 nM)... |
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T36074 |
S-NEPC
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Cytochrome P450 metabolites of arachidonic acid, such as 11(12)-EpETrE and 14(15)-EpETrE have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) cata... |
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T36370 |
4-Methylumbelliferyl-α-L-Iduronide (free acid)
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4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and hepa... |
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T36504 |
STY-BODIPY
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STY-BODIPY,Styrene-BODIPY |
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STY-BODIPY is a styrene-conjugated fluorogenic probe for radical-trapping antioxidant (RTA) activity.1 Co-autoxidation of the STY-BODIPY signal carrier and a hydrocarbon co-substrate can be quantified by monitoring the l... |
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T83941 |
Mag-Fura-2 AM
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Mag-Fura-2 AM, a cell-permeable fluorescent compound, serves as a selective indicator for magnesium ions (Mg2+), demonstrating significant preference for Mg2+ over other bivalent ions including zinc (Zn2+), copper (Cu2+)... |
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T36650 |
Ansatrienin B
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Ansatrienin B is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis., In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 21 nM... |
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T37191 |
Mu-6S-Palm-β-Glc
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Mu-6S-Palm-β-Glc is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. Mu-6S-... |
