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Search Results for " multiprotein "

ターゲット

1

阻害剤

15

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T22884 JW 67 Wnt/beta-catenin
JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-00693 EDF1 Protein, Human, Recombinant (His) Human E. coli
Endothelial Differentiation-Related Factor 1 (EDF1) is a 148 amino acid transcriptional coactivator that contains 1 HTH cro/C1-type DNA-binding domain. It has been postulated that the protein functions as a bridging mole...
TMPH-01472 HDAC11 Protein, Human, Recombinant (GST) Human E. coli
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcrip...
TMPH-00106 TBP1 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) Arabidopsis thaliana E. coli
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a ro...
TMPH-01090 CBX8 Protein, Human, Recombinant (His) Human E. coli
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex...
TMPY-03395 PC4/SUB1 Protein, Human, Recombinant (His) Human E. coli
SUB1 belongs to the transcriptional coactivator PC4 family. It is a general coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptio...
TMPY-03431 HDAC4 Protein, Human, Recombinant (aa 612-1084) Human Baculovirus Insect Cells
HDAC4 (histone deacetylase 4), belongs to class II of the histone deacetylase/AcuC/APhA family. Histone Deacetylases (HDACs) are a group of enzymes closely related to sirtuins. They catalyze the removal of acetyl groups ...
TMPJ-01297 WIBG Protein, Human, Recombinant (His) Human E. coli
Partner of Y14 and Mago (WIBG) is a key regulator of the Exon Junction Complex (EJC). EJC is a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs, is a positional landmarker for ...
TMPH-02571 CD9 Protein, Mouse, Recombinant (His) Mouse E. coli
Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays...
TMPJ-01124 PDIA6 Protein, Human, Recombinant (His) Human HEK293 Cells
Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and br...
TMPY-01187 Rac1 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal re...
TMPH-01621 BRCC3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes...
TMPY-02889 IZUMO4 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Izumo is a sperm membrane protein that plays a key role in the fusion in the mouse. It has an Immunoglobulin (Ig) domain and an N-terminal domain for which neither the functions nor homologous sequences are known. Up to ...
TMPH-02217 SMARCA4 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic acti...
TMPH-01263 PRKN Protein, Human, Recombinant (His & SUMO) Human E. coli
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...
TMPH-02631 PRKN Protein, Mouse, Recombinant (GST) Mouse E. coli
Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Substrates include SYT11 and VDAC1. Other substrates are BCL2, CCNE1, GPR37, ...
EDF1 Protein, Human, Recombinant (His)
TMPJ-00693
Species: Human
Expression System: E. coli
HDAC11 Protein, Human, Recombinant (GST)
TMPH-01472
Species: Human
Expression System: E. coli
TBP1 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)
TMPH-00106
Species: Arabidopsis thaliana
Expression System: E. coli
CBX8 Protein, Human, Recombinant (His)
TMPH-01090
Species: Human
Expression System: E. coli
PC4/SUB1 Protein, Human, Recombinant (His)
TMPY-03395
Species: Human
Expression System: E. coli
HDAC4 Protein, Human, Recombinant (aa 612-1084)
TMPY-03431
Species: Human
Expression System: Baculovirus Insect Cells
WIBG Protein, Human, Recombinant (His)
TMPJ-01297
Species: Human
Expression System: E. coli
CD9 Protein, Mouse, Recombinant (His)
TMPH-02571
Species: Mouse
Expression System: E. coli
PDIA6 Protein, Human, Recombinant (His)
TMPJ-01124
Species: Human
Expression System: HEK293 Cells
Rac1 Protein, Human, Recombinant (GST)
TMPY-01187
Species: Human
Expression System: Baculovirus Insect Cells
BRCC3 Protein, Human, Recombinant (His & SUMO)
TMPH-01621
Species: Human
Expression System: E. coli
IZUMO4 Protein, Human, Recombinant (hFc)
TMPY-02889
Species: Human
Expression System: HEK293 Cells
SMARCA4 Protein, Human, Recombinant (His)
TMPH-02217
Species: Human
Expression System: P. pastoris (Yeast)
PRKN Protein, Human, Recombinant (His & SUMO)
TMPH-01263
Species: Human
Expression System: E. coli
PRKN Protein, Mouse, Recombinant (GST)
TMPH-02631
Species: Mouse
Expression System: E. coli