Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1.
説明 | JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1. |
ターゲット&IC50 | Wnt:1.17μM |
分子量 | 394.38 |
分子式 | C21H18N2O6 |
CAS No. | 442644-28-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (152.14 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JW 67 442644-28-2 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin inhibit Wnt Inhibitor CK1 complex JW-67 β-catenin GSK-3b JW67 AXIN multiprotein APC inhibitor