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T8452 |
Dantrolene
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|
Others
|
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Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. |
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T3086 |
Mesoridazine Besylate
|
Mesoridazine benzenesulfonate,Serentil |
Dopamine Receptor
,
5-HT Receptor
|
|
Mesoridazine Besylate (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a metabolite of thioridazine. |
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T7943 |
Fluphenazine decanoate
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|
Dopamine Receptor
|
|
Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. |
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T83648 |
Tenilapine
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|
Others
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|
Tenilapine is a neuroleptic compound that can be used to study atypical antipsychotics. |
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T7561 |
Benzetimide hydrochloride
|
R4929 |
AChR
|
|
Benzetimide hydrochloride (R4929) is an antagonist of muscarinic acetylcholine receptor.treatment neuroleptic-induced parkinsonism. |
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T11121 |
Duoperone
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Others
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Duoperone is a neuroleptic agent. Duoperone shows antiemetic activity in animal models. |
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T6398 |
Azaperone
|
R-1929,Fluoperidol,Stresnil,NSC 170976,Suicalm |
Others
,
Dopamine Receptor
|
|
Azaperone (Fluoperidol) is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. |
|
T14830 |
Bromperidol
|
R-11333 |
5-HT Receptor
|
|
Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic. Which is used as an antipsychotic in the treatment of schizophrenia. |
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T1478 |
Ondansetron hydrochloride dihydrate
|
SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride |
5-HT Receptor
|
|
Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, a... |
|
T0025 |
Haloperidol
|
Aloperidin,Serenace,Haldol |
Dopamine Receptor
,
5-HT Receptor
|
|
Haloperidol (Serenace) is a highly potent neuroleptic by relieving nervous through the depression of nerve function. In addition, haloperidol has shown about 50-fold efficacy than chlorpromazine, another antipsychotic dr... |
|
T67811 |
Tefludazine
|
|
|
|
Tefludazine, a novel neuroleptic with a benzindone structure, is a compound with good oral activity and antagonistic effects on dopamine and 5-hydroxytryptamine receptors. Tefludazine has shown potent dopamine (DA) antag... |
|
T0455 |
Clozapine
|
HF 1854,LX 100-129 |
Dopamine Receptor
,
Adrenergic Receptor
,
AChR
|
|
Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a... |
|
T34731 |
SU 23397
|
SU-23397,SU23397 |
|
|
SU 23397 is a structurally unique neuroleptic agent. |
|
T35315 |
Zoloperone
|
Zoloperonum,LR511,LR 511,LR-511 |
|
|
Zoloperone is a neuroleptic. |
|
T0445L1 |
Promethazine hibenzate
|
D-08768,D08768,D 08768 |
|
|
Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. |
|
T34169 |
Prothipendyl
|
|
|
|
Prothipendyl is a neuroleptic azaphenothiazine. |
|
T26360L |
Benperidol Hydrochloride
|
|
|
|
Benperidol Hydrochloride is a potent D2/D4 dopamine receptor antagonist, used as antipsychotic and neuroleptic. |
|
T26472 |
A23887
|
A-23887,A 23887 |
|
|
A23887 is a potentially neuroleptic tetracyclic spiro amine that has affinity for dopamine D-2 receptors. |
|
T34061 |
Picobenzide
|
M 14012-4,MA 14012 |
|
|
Picobenzide, also known as M-14012-4, is a neuroleptic agent, |
|
T69825 |
Dexetimide HCl
|
|
|
|
Dexetimide HCl is a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide. |
|
T15104 |
Dexetimide
|
(+)-Benzetimide,Dexbenzetimide,(S)-(+)-Dexetimide |
Others
|
|
Dexetimide ((+)-Benzetimide) is a high-affinity antagonist of the muscarinic receptor. It is a persistent anticholinergic agent and can be used to treat neuroleptic-induced parkinsonism. |
|
T71926 |
Melperone hydrochloride
|
|
|
|
Melperone hydrochloride is a butyrophenone neuroleptic and an inhibitor of the CYP2D6 catalyzed O-demethylation of venlafaxine. |
|
T15743 |
Levomepromazine
|
Methotrimeprazine |
Others
|
|
Methotrimeprazine is an orally available neuroleptic agent. It is commonly used to relieve nausea and vomiting in palliative care settings. Levomepromazine has antagonist actions at multiple neurotransmitter receptor sit... |
|
T15026 |
Cyamemazine
|
|
5-HT Receptor
|
|
Cyamemazine, contains the phenothiazine chromophore, is a neuroleptic agent used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki: 12 nM), 5-HT2A (Ki: 1.5 nM) and 5-HT2C (Ki: 75 nM) receptors antagonist with antipsych... |
|
T70425 |
Amiperone
|
|
|
|
Amiperone is a neuroleptic drug. It prolonged the latency and reduced the frequency of the noise escape response rate in rats. It also inhibited lever-press response and reduced the shock-avoidance rate at very low dose ... |
|
T61006 |
Tropatepine
|
|
|
|
Tropatepine is an orally active antagonist of anticholinergic muscarinic. Tropatepine is an antiparkinsonian agent that can be used to combat against extrapyramidal syndrome caused by neuroleptic drugs [1][2]. |
|
T78535 |
Trans-Clopenthixol dihydrochloride
|
(E)-Clopenthixol dihydrochloride |
Parasite
|
|
Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced... |
|
T60943 |
Tiapride
|
|
|
|
Tiapride is an atypical neuroleptic agent without propensity for causing catalepsy and sedation. Tiapride is a selective antagonist of dopamine D2-receptor with IC 50 values of 1440, 45.8, >100, and 11.7 μM for D1; D2; D... |
|
T69129 |
Clozapine HCl
|
|
|
|
Clozapine HCl is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serot... |
