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T15500 |
HPi1
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Others
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Antibacterial
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HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri... |
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T5518 |
N-acetylcysteine amide
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Reactive Oxygen Species
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ROS
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N-Acetylcysteine amide is a thiol antioxidant and neuroprotective agent that can permeate cell membranes and the blood-brain barrier. |
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T38253 |
Lauroyl-L-carnitine (chloride)
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Lauroyl-L-carnitine Hydrochloride |
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Lauroyl-L-carnitine (chloride) (Lauroyl-L-carnitine Hydrochloride), an acylcarnitine and surfactant, has been used to permeate porcine intestinal cells to deliver the polar fluorescent probe fluorescent yellow. |
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T37482 |
Diclofenac methyl ester
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Others
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Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac . It is more soluble than diclofenac acid in isopropylmyristate. Diclofenac methyl ester does not perme... |
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T78392 |
Zinquin ethyl ester
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Zinquin ethyl ester, a lipophilic and zinc-sensitive fluorophore derivative of Zinquin, exhibits specificity for zinc ions and possesses the ability to permeate cell membranes [1]. |
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T78973 |
DCN-83
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Parasite
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DCN-83, a potent anti-leishmanial compound, exhibits its highest efficacy against the amastigote form, achieving an IC50 value of 0.71 μM. It also possesses the ability to permeate the blood-brain barrier, impacting the ... |
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T16565 |
Ppc-1
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Others
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Ppc-1 is a chemical compound known for its inhibitory effects on the Gram-negative periodontopathogen Porphyromonas gingivalis. It acts as a mitochondrial uncoupler, enhancing mitochondrial oxygen consumption without aff... |
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T72715 |
JNK3 inhibitor-4
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JNK3 Inhibitor-4, a potent 2-aryl-1-pyrimidinyl-1H-imidazole-5-yl acetonitrile derivative, demonstrates a strong inhibitory effect on JNK3 with an IC 50 value of 1.0 nM. It exhibits exceptional selectivity against JNK3 w... |
