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Search Results for " purines "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T21588	Olomoucine		ERK , CDK
	Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 µM, respectively. Olomoucine regulates cell cycle and exhibits an...		ERK , CDK
TNU0909	1,9-Dihydro-9-methyl-6H-purin-6-one
	1,9-Dihydro-9-methyl-6H-purin-6-one belongs to Heterocyclic Compounds - Purines.
T22409	Proguanil	chloroguanide,chlorguanide	Others
	Proguanil, a prophylactic antimalarial drug, inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of pyrimidines and purines, which are essential for DNA synthesis and cell multiplication...		Others
TNU1134	7-benzyl-3-methylxanthine
	7-benzyl-3-methylxanthine belongs to Heterocyclic Compounds - Purines.
TNU1133	1,7-Dibenzyl-3-methylxanthine
	1,7-Dibenzyl-3-methylxanthine belongs to Heterocyclic Compounds - Purines.
TNU0907	6-Chloro-9-methyl-9H-purine
	Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Electrophiles
TNU1262	1H-Imidazo[4,5-d]pyridazin-7-amine
	1H-Imidazo[4,5-d]pyridazin-7-amine belongs to Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Nucleoside bases.
TNU0908	9-Methyladenine
	Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Nucleophiles
TNU0900	2-Amino-6-ethoxypurine
	Heterocyclic Compounds –Purines; Intermediates and Building Blocks - Nucleoside bases
TNU1104	6-Chloro-2-(trifluoromethyl)-9H-purine
	Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Nucleoside bases; Multi-functional; Scaffolds and Templates
TNU0611	4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine
	Heterocyclic compound –purines, intermediate and building block; Used for modified nucleosides and nucleic acids
T63240	Lometrexol disodium
	Lometrexol (DDATHF) disodium is a potent inhibitor of human serine hydroxymethyltransferase 1/2 (hSHMT1/2) and antifolate, which reduces the activity of glycinamide ribonucleotide formyltransferase (GARFT) without causin...
T35413	(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)
	(6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism. Its metabolites participate in...

Compounds

1,9-Dihydro-9-methyl-6H-purin-6-one

Synonym: chloroguanide,chlorguanide

Target: Others

7-benzyl-3-methylxanthine

TNU1134

Synonym:

Target:

1,7-Dibenzyl-3-methylxanthine

TNU1133

Synonym:

Target:

6-Chloro-9-methyl-9H-purine

TNU0907

Synonym:

Target:

1H-Imidazo[4,5-d]pyridazin-7-amine

2-Amino-6-ethoxypurine

TNU0900

Synonym:

Target:

6-Chloro-2-(trifluoromethyl)-9H-purine

TNU1104

Synonym:

Target:

4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine

(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)

T35413

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T4746	Purine	7H-Imidazo(4,5-d)pyrimidine	Others , Endogenous Metabolite
	Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines f...		Others , Endogenous Metabolite

天然物製品

Purine

T4746

Synonym: 7H-Imidazo(4,5-d)pyrimidine

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01862	PFAS Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonu...
TMPJ-00725	HGPRT Protein, Human, Recombinant (His)	Human	E. coli
	Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed pur...
TMPH-00120	Ribonuclease clavin Protein, Aspergillus clavatus, Recombinant (His & Myc)	Aspergillus clavatus	E. coli
	Clavin has the same substrate specificity as alpha-sarcin. It is specific for purines in both single- and double-stranded RNA. Its toxic action on eukaryotic cells is the result of cleavage of a single phosphodiester bon...
TMPJ-00989	MTHFS Protein, Human, Recombinant (His)	Human	E. coli
	5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contr...
TMPJ-00484	SHMT1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to g...
TMPJ-01308	ITPase Protein, Human, Recombinant (His)	Human	E. coli
	Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphat...