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Search Results for " telomere "

ターゲット

5

阻害剤

10

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T8647 BCH001 DNA/RNA Synthesis
BCH001 is a specific small-molecule inhibitor of PAPD5.
T26892 Braco-19 Antiviral , Telomerase
Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in h...
T62915 Dot1L-IN-7
Dot1L-IN-7 (compound 25) is a selective and potent inhibitor of telomere silencing 1-like protein (DOT1L) (IC50: 1.0 μM).Dot1L-IN-7 selectively kills MLL-AF9 and does not affect the growth of E2A-HLF cells.
T82667 CRT0063465
CRT0063465 is a ligand for both human Phosphoglycerate Kinase 1 (PGK1) and the stress sensor protein DJ-1, exhibiting a dissociation constant (Kd) of 24 μM for PGK1. Additionally, it influences the composition of the she...
T63072 ETP-47037
ETP-47037 is a potent inhibitor of the PI3Kα isoform (IC50: 0.99 nM) and inhibits the PI3Kβ (IC50: 49.2 nM), PI3Kδ (IC50: 7.13 nM) and PI3Kγ (IC50: 49.1 nM) isoforms. ETP-47037 has potential for telomere protection chemo...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-00518 SBDS Protein, Human, Recombinant (His) Human E. coli
The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disor...
TMPY-00452 SBDS Protein, Mouse, Recombinant (His) Mouse E. coli
The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disor...
TMPY-02298 ACYP2 Protein, Human, Recombinant (GST) Human E. coli
Recent genome-wide association studies have identified genetic variants in ACYP2 and WFS1 that are associated with cisplatin-induced ototoxicity. We sought to explore the role of these genetic susceptibility factors to c...
TMPY-02399 TRF1 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Telomeric repeat binding factor 1 (TRF1), also known as TERF1, the shelterin complex, which modulates the telomere structures. TRF1 protein structure contains a C-terminal Myb motif, a dimerization domain near its N-term...
TMPH-02183 CCT2 Protein, Human, Recombinant (His & SUMO) Human E. coli
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating t...
TMPJ-00516 OBhFc1 Protein, Human, Recombinant (His) Human E. coli
CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA ...
TMPY-03521 DcR3 Protein, Human, Recombinant (hFc) Human Baculovirus Insect Cells
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor ...
TMPH-01237 POLQ Protein, Human, Recombinant (E. coli, His) Human E. coli
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathw...
TMPH-01238 POLQ Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathw...
TMPH-01267 RNF13 Protein, Human, Recombinant (His & Myc) Human E. coli
E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair protein...
カタログ番号 製品名
L8200 Anti-Aging Compound Library

3279 compounds
A unique collection of 3279 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS);