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カタログ番号 | 製品名 | 別名 | ターゲット |
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T8647 | BCH001 | DNA/RNA Synthesis | |
BCH001 is a specific small-molecule inhibitor of PAPD5. | |||
T26892 | Braco-19 | Antiviral , Telomerase | |
Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in h... | |||
T62915 | Dot1L-IN-7 | ||
Dot1L-IN-7 (compound 25) is a selective and potent inhibitor of telomere silencing 1-like protein (DOT1L) (IC50: 1.0 μM).Dot1L-IN-7 selectively kills MLL-AF9 and does not affect the growth of E2A-HLF cells. | |||
T82667 | CRT0063465 | ||
CRT0063465 is a ligand for both human Phosphoglycerate Kinase 1 (PGK1) and the stress sensor protein DJ-1, exhibiting a dissociation constant (Kd) of 24 μM for PGK1. Additionally, it influences the composition of the she... | |||
T63072 | ETP-47037 | ||
ETP-47037 is a potent inhibitor of the PI3Kα isoform (IC50: 0.99 nM) and inhibits the PI3Kβ (IC50: 49.2 nM), PI3Kδ (IC50: 7.13 nM) and PI3Kγ (IC50: 49.1 nM) isoforms. ETP-47037 has potential for telomere protection chemo... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-00518 | SBDS Protein, Human, Recombinant (His) | Human | E. coli |
The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disor... | |||
TMPY-00452 | SBDS Protein, Mouse, Recombinant (His) | Mouse | E. coli |
The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disor... | |||
TMPY-02298 | ACYP2 Protein, Human, Recombinant (GST) | Human | E. coli |
Recent genome-wide association studies have identified genetic variants in ACYP2 and WFS1 that are associated with cisplatin-induced ototoxicity. We sought to explore the role of these genetic susceptibility factors to c... | |||
TMPY-02399 | TRF1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Telomeric repeat binding factor 1 (TRF1), also known as TERF1, the shelterin complex, which modulates the telomere structures. TRF1 protein structure contains a C-terminal Myb motif, a dimerization domain near its N-term... | |||
TMPH-02183 | CCT2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating t... | |||
TMPJ-00516 | OBhFc1 Protein, Human, Recombinant (His) | Human | E. coli |
CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA ... | |||
TMPY-03521 | DcR3 Protein, Human, Recombinant (hFc) | Human | Baculovirus Insect Cells |
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor ... | |||
TMPH-01237 | POLQ Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathw... | |||
TMPH-01238 | POLQ Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathw... | |||
TMPH-01267 | RNF13 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair protein... |
カタログ番号 | 製品名 | ||
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L8200 | Anti-Aging Compound Library | 3279 compounds | |
A unique collection of 3279 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS); |