Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.
説明 | Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation. |
In vitro | CaD inhibited abnormal cell proliferation. high glucose (HG) treatment also significantly enhanced HVUEC migration compared to the control treatment. In contrast, CaD treatment partially inhibited HUVEC migration compared to HG exposure. HG?treated HUVECs exhibited increased FITC?BSA permeability compared to control cells cultured in medium alone; however, CaD application prevented the HG?induced increase in FITC?BSA permeability and suppressed HG?induced overexpression of endothelial markers (VEGF, VEGFR?2, endocan) and inflammation markers (ICAM?1, MCP?1, PTX3) in HUVECs. CaD has angioprotective properties and protects endothelial cells partly by ameliorating HG?induced inflammation[1]. |
細胞研究 | HUVECs were seeded in 96-well culture plates (1×10^4 cells/well). Following 24 h, the control or experimental medium was added. At 12, 24, 48 and 72 h, 10 μl CCK-8 reagent was added to each well for 1 h. Absorbance values were recorded at a wavelength of 450 nm using a microplate reader[1]. |
分子量 | 229.2 |
分子式 | C6H5O5SCa0.5 |
CAS No. | 20123-80-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (218.15 mM)
You can also refer to dose conversion for different animals. 詳細
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Calcium dobesilate 20123-80-2 Apoptosis Others inhibit Inhibitor inhibitor