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Aromatase

Aromatase is the enzyme that catalyzes a key aromatization step in the synthesis of estrogen. It converts the enone ring of androgen precursors such as testosterone, to a phenol, completing the synthesis of estrogen.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T3390 Obacunone 751-03-1 98%
Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compo...
T7197 Fadrozole 102676-47-1 98%
Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)
T7556 Fadrozole hydrochloride 102676-31-3 98%
Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.
T6917 Oleuropein 32619-42-4 98%
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
T3899 Calceolarioside B 105471-98-5 100%
Calceolarioside B (Desrhamnosyl isoacteoside) displays inhibition of aromatase. Calceolarioside B displays inhibition of human recombinant PKCalpha.
T27320 Finrozole 160146-17-8 100%
Finrozole (MPV 2213ad) is a novel selective aromatase inhibitor that is partially reversible for breast development.
T23549 YM 511 148869-05-0 100%
YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively...
T26322L (-)-Vorozole 132042-69-4 97.14%
(-)-Vorozole is an orally active non-steroidal aromatase inhibitor with potency and selectivity. (-)-Vorozole has demonstrated antitumor activity in in vivo expe...
T2O2744 Alpha-Naphthoflavone 604-59-1 98%
alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.
T60664 Atamestane 96301-34-7 98.41%
Atamestane is a competitive, irreversible inhibitor of estrogen biosynthesis, a specific aromatase inhibitor that selectively blocks estrogen biosynthesis result...
T1103 Aminoglutethimide 125-84-8 98.81%
Aminoglutethimide (BA-16038), an aromatase inhibitor, is used in the therapy of advanced BREAST Y.
T71708 Minamestane 105051-87-4 99.04%
Minamestane is a novel irreversible aromatase inhibitor.Minamestane induces time-dependent inhibition of human placental aromatase with a half-life of 4 minutes ...
T27918 LY 43578 26766-35-8 99.62%
LY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (I...
T4281 Endoxifen 110025-28-0 99.66%
(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It ...
T1590 Letrozole 112809-51-5 99.68%
Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.
T1692 3-(3,4-Dimethoxyphenyl)propanoic acid 2107-70-2 99.68%
3-(3,4-Dimethoxyphenyl)propanoic acid (3,4-Dimethoxyhydrocinnamic acid) is an orally active short-chain fatty acid (SCFAs). It promotes γ-globin gene expression ...
T1587 Exemestane 107868-30-4 99.73%
Exemestane (EXE) is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.
T26322 Vorozole 129731-10-8 99.89%
Vorozole (R83842) is an orally active, potent, and selective nonsteroidal aromatase inhibitor.Vorozole exhibits antitumor activity in vivo and may be used in the...
T0530 Flavanone 487-26-3 99.95%
Flavanone (2-Phenylchroman-4-one)s from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interve...
T0393 Anastrozole 120511-73-1 99.96%
Anastrozole (ZD1033)(ZD1033), a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM), has no obvious effect on adrenocorticoid hormone synthesi...
Obacunone
T3390
Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compo...
Fadrozole
T7197
Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)
Fadrozole hydrochloride
T7556
Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish.
Oleuropein
T6917
Oleuropein is an antioxidant polyphenol isolated from olive leaf.
Calceolarioside B
T3899
Calceolarioside B (Desrhamnosyl isoacteoside) displays inhibition of aromatase. Calceolarioside B displays inhibition of human recombinant PKCalpha.
Finrozole
T27320
Finrozole (MPV 2213ad) is a novel selective aromatase inhibitor that is partially reversible for breast development.
YM 511
T23549
YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively...
(-)-Vorozole
T26322L
(-)-Vorozole is an orally active non-steroidal aromatase inhibitor with potency and selectivity. (-)-Vorozole has demonstrated antitumor activity in in vivo expe...
alpha-Naphthoflavone
T2O2744
alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.
Atamestane
T60664
Atamestane is a competitive, irreversible inhibitor of estrogen biosynthesis, a specific aromatase inhibitor that selectively blocks estrogen biosynthesis result...
Aminoglutethimide
T1103
Aminoglutethimide (BA-16038), an aromatase inhibitor, is used in the therapy of advanced BREAST Y.
Minamestane
T71708
Minamestane is a novel irreversible aromatase inhibitor.Minamestane induces time-dependent inhibition of human placental aromatase with a half-life of 4 minutes ...
LY 43578
T27918
LY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (I...
Endoxifen
T4281
(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It ...
Letrozole
T1590
Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.
3-(3,4-Dimethoxyphenyl)propanoic acid
T1692
3-(3,4-Dimethoxyphenyl)propanoic acid (3,4-Dimethoxyhydrocinnamic acid) is an orally active short-chain fatty acid (SCFAs). It promotes γ-globin gene expression ...
Exemestane
T1587
Exemestane (EXE) is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor.
Vorozole
T26322
Vorozole (R83842) is an orally active, potent, and selective nonsteroidal aromatase inhibitor.Vorozole exhibits antitumor activity in vivo and may be used in the...
Flavanone
T0530
Flavanone (2-Phenylchroman-4-one)s from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interve...
Anastrozole
T0393
Anastrozole (ZD1033)(ZD1033), a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM), has no obvious effect on adrenocorticoid hormone synthesi...
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