ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T6307 | Lubiprostone | 136790-76-6 | 98% |
|
| Lubiprostone, an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation. | ||||
| T0275 | Meticrane | 1084-65-7 | 98% |
|
| Meticrane is a sulphonamide-derivative with thiazide-like diuretic activity. | ||||
| T4811 | D-Alanine | 338-69-2 | 98% |
|
| Alanine is a nonessential amino acid made in the body from the conversion of the carbohydrate pyruvate or the breakdown of DNA and the dipeptides carnosine and a... | ||||
| T50082 | Org 25543 | 363628-88-0 | 98% |
|
| Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain. | ||||
| T5225 | Hypotaurine | 300-84-5 | 98% |
|
| Hypotaurine, an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. | ||||
| T0954 | Halothane | 151-67-7 | 98% |
|
| Halothane is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adeq... | ||||
| T16533 | Picrotin | 21416-53-5 | 98% |
|
| Picrotin is an inhibitor of glycine receptors. Picrotin blocks α2 GlyR, α1 GlyR, and α3 GlyR and can be used in studies about neurotransmission. | ||||
| T13059 | T16Ainh-A01 | 552309-42-9 | 98% |
|
| T16Ainh-A01 is a potent inhibitor of TMEM16A Chloride channel, inhibiting TMEM16A-mediated chloride currents (IC50 of 1 µM),and functions as a calcium-activated ... | ||||
| T0019 | Betaine chloride | 590-46-5 | 98% |
|
| Betaine hydrochloride is an acidic form of betaine, a vitamin-like substance observed in grains and other foods; gains the amplification of DNA by decreasing the... | ||||
| T7638 | NPPB | 107254-86-4 | 98% |
|
| NPPB is a chloride channel blocker with IC50 of 80 nM . | ||||
| T2498 | Adjudin | 252025-52-8 | 98% |
|
| Adjudin is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway. | ||||
| T16535 | Picrotoxinin | 17617-45-7 | 98% |
|
| Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant p... | ||||
| T36585 | Isodeoxycholic Acid | 566-17-6 | 98% |
|
| Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration t... | ||||
| T1125 | Shikonin | 517-89-5 | 98% |
|
| Shikonin is an TMEM16A chloride channel inhibitor (IC50: 6.5 μM). Shikonin is also a selective PKM2 inhibitor and can also suppress activation of the NF-κB pathw... | ||||
| T15233 | Endovion | 265646-85-3 | 98% |
|
| Endovion is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is also the specific VRAC/VSOAC blocker. | ||||
| T15192 | Eact | 461000-66-8 | 98% |
|
| Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception an... | ||||
| T26630 | Ani9 | 356102-14-2 | 98% |
|
| Ani9 is a high selective blocker of Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) with an IC50 of 77 nM and can be used in studies about ANO1 and the tre... | ||||
| T21615 | Guanidinoethyl sulfonate | 543-18-0 | 98% |
|
| Guanidinoethyl sulfonate is a competitive glycine receptor antagonist. | ||||
| T12788 | R(+)-IAA-94 | 54197-31-8 | 98% |
|
| R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and b... | ||||
| TN1035 | Irisolidone | 2345-17-7 | 98% |
|
| Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM. | ||||
