ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
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DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T11662L | INT-777 | 1199796-29-6 | 98% |
|
| INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/... | ||||
| TP1949L | PEN (human) aceate | 98% |
|
|
| PEN (human) aceate, one of the most abundant hypothalamic neuropeptide and derived from the proprotein ProSAAS, is an endogenous ligand of GPR83. | ||||
| T29078 | Ursodeoxycholic acid sodium | 2898-95-5 | 98% |
|
| Ursodeoxycholic acid sodium is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts a... | ||||
| T5077 | Deoxycholic acid sodium salt | 302-95-4 | 98% |
|
| Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity. | ||||
| T2968 | Hyodeoxycholic acid | 83-49-8 | 98% |
|
| Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia. | ||||
| T1824 | TGR5 Receptor Agonist | 1197300-24-5 | 98% |
|
| TGR5 is a potent TGR5(GPCR19) agonist. | ||||
| T8818 | TC-G 1005 | 1415407-60-1 | 98% |
|
| TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and re... | ||||
| T4352 | SB756050 | 447410-57-3 | 98% |
|
| SB756050 is a specific TGR5 agonist. | ||||
| T4083 | BAR501 | 1632118-69-4 | 98% |
|
| BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM). | ||||
| T2965 | Deoxycholic acid | 83-44-3 | 98% |
|
| Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent t... | ||||
| T7428 | SBI-115 | 882366-16-7 | 98% |
|
| SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5 | ||||
| TQ0252 | BAR502 | 1612191-86-2 | 98% |
|
| BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM). | ||||
| T8752 | BAR 501 impurity | 1632118-70-7 | 98% |
|
| BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501... | ||||
