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Glucocorticoid Receptor

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind. The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T1559 Betamethasone dipropionate 5593-20-4 98%
Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory ...
T0208 Prednisolone disodium phosphate 125-02-0 98%
Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties.
T3316 Fluorometholone 426-13-1 98%
Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon)...
T1561 Clobetasol propionate 25122-46-7 98%
Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expre...
T4277 Osilodrostat 928134-65-0 98%
Osilodrostat (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).
T0188 Fluticasone (propionate) 80474-14-2 98%
Fluticasone propionate, derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist....
T1127 Beclometasone dipropionate 5534-09-8 98%
Beclomethasone Dipropionate is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface re...
T22818 GSK9027 1229096-88-1 98%
GSK9027 is a nonsteroidal glucocorticoid receptor (GR) agonist.GSK9027 is a partial agonist on the 2×GRE reporter gene compared to dexamethasone and is less acti...
T8396 Prednisone acetate 125-10-0 98%
Prednisone acetate is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory.
T0261 Amcinonide 51022-69-6 98%
Amcinonide is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.
T0107 Halcinonide 3093-35-4 98%
Halcinonide, a high-efficiency corticosteroid, is served as an anti-inflammatory agent used in topical preparations.
T1541 Drospirenone 67392-87-4 98%
Drospirenone is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.
T1163 Betamethasone valerate 2152-44-5 98%
Betamethasone Valerate is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions.
T2548 Diflorasone 2557-49-5 98%
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by dif...
T0034 Cortisone acetate 50-04-4 98%
Cortisone Acetate is the acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal...
T0977 Medrysone 2668-66-8 98%
Medrysone is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with ...
T1124 Flumethasone 2135-17-3 98%
Flumethasone is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
T6503 Fluorometholone Acetate 3801-06-7 98%
Fluorometholone Acetate is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
T1666 Fludrocortisone acetate 514-36-3 98%
Fludrocortisone, a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of ...
T1284 Megestrol acetate 595-33-5 98%
Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. ...
Betamethasone dipropionate
T1559
Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory ...
Prednisolone disodium phosphate
T0208
Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties.
Fluorometholone
T3316
Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon)...
Clobetasol propionate
T1561
Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expre...
Osilodrostat
T4277
Osilodrostat (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).
Fluticasone (propionate)
T0188
Fluticasone propionate, derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist....
Beclometasone dipropionate
T1127
Beclomethasone Dipropionate is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface re...
GSK9027
T22818
GSK9027 is a nonsteroidal glucocorticoid receptor (GR) agonist.GSK9027 is a partial agonist on the 2×GRE reporter gene compared to dexamethasone and is less acti...
Prednisone acetate
T8396
Prednisone acetate is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory.
Amcinonide
T0261
Amcinonide is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.
Halcinonide
T0107
Halcinonide, a high-efficiency corticosteroid, is served as an anti-inflammatory agent used in topical preparations.
Drospirenone
T1541
Drospirenone is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.
Betamethasone valerate
T1163
Betamethasone Valerate is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions.
Diflorasone
T2548
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by dif...
Cortisone acetate
T0034
Cortisone Acetate is the acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal...
Medrysone
T0977
Medrysone is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with ...
Flumethasone
T1124
Flumethasone is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
Fluorometholone Acetate
T6503
Fluorometholone Acetate is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
Fludrocortisone acetate
T1666
Fludrocortisone, a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of ...
Megestrol acetate
T1284
Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. ...
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