store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylation. Glucagon (1-29), bovine, human, porcine hydrochloride(Porcine glucagon hydrochloride) stimulates gluconeogenesis.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 18,500 | |||
5 mg | 在庫あり | ¥ 44,500 | |||
10 mg | 在庫あり | ¥ 66,500 | |||
25 mg | 在庫あり | ¥ 114,500 | |||
50 mg | 在庫あり | ¥ 167,500 | |||
100 mg | 在庫あり | ¥ 226,000 | |||
500 mg | 在庫あり | ¥ 452,500 |
説明 | Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylation. Glucagon (1-29), bovine, human, porcine hydrochloride(Porcine glucagon hydrochloride) stimulates gluconeogenesis. |
In vitro | Glucagon stimulates both hepatic kisspeptin1 production and gluconeogenesis. Upon binding to its receptor Gcgr, Glucagon activates cAMP-PKA signaling to stimulate hepatic glucose production (HGP) and cause hyperglycemia. Glucagon (100 nM) increases the phosphorylation of HNF4α. Glucagon (100 nM) represses CYP7A1 mRNA expression in human primary hepatocytes [3]. |
In vivo | Glucagon (20 μg/kg) increases glycemia and does not stimulate insulin secretion in ambient-fed mice. High-dose (1 mg/kg) Glucagon lowers glycemia compared with PBS control and stimulates insulin secretion in ambient-fed mice [4]. |
別名 | Porcine glucagon hydrochloride, Glucagon hydrochloride |
分子量 | 3519.21 |
分子式 | C153H225N43O49S.ClH |
CAS No. | 28270-04-4 |
store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Glucagon (1-29), bovine, human, porcine hydrochloride 28270-04-4 Endocrinology/Hormones GPCR/G Protein Glucocorticoid Receptor Glucagon Receptor Porcine glucagon peptide hormone gluconeogenesis Inhibitor pancreatic α Glucagon (129), bovine, human, porcine hydrochloride GCGR inhibit Glucagon Hydrochloride HNF4α HNF-4 Glucagon (1-29), bovine, human, porcine Porcine glucagon Hydrochloride Porcine glucagon hydrochloride Glucagon hydrochloride Glucagon , bovine, human, porcine Hydrochloride Glucagon (1 29), bovine, human, porcine hydrochloride inhibitor