Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 µM. TG6-129 reduces the expression of COX-2, IL-1β, IL-6, IL-12, IL-23 and TNF-α induced by the EP2-selective agonist butaprost in P388D1 macrophages.
説明 | TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 µM. TG6-129 reduces the expression of COX-2, IL-1β, IL-6, IL-12, IL-23 and TNF-α induced by the EP2-selective agonist butaprost in P388D1 macrophages. |
別名 | TG6 129 |
分子量 | 491.58 |
分子式 | C20H18FN5O3S3 |
CAS No. | 1164464-14-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (111.88 mM)
You can also refer to dose conversion for different animals. 詳細
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TG6-129 1164464-14-5 GPCR/G Protein Immunology/Inflammation Prostaglandin Receptor TG6 129 TG6129 inhibit Inhibitor TG-6-129 inhibitor