Serine Protease

Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins, in which serine serves as the nucleophilic amino acid at the (enzyme's) active site. They are found ubiquitously in both eukaryotes and prokaryotes.

Cat. No.	製品名	CAS No.	Purity
T8602	2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA6-BENZO[D]ISOTHIAZOL-3-ONE	13947-21-2	98%
T8602	2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA6-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).
T8802	2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-	80499-32-7	98%
T8802	Trypsin inhibitor (human urine urinastatin protein moiety)， as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine or...
T8563	2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one	1234707-32-4	98%
T8563	2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.
T3359	Aprotinin	9087-70-1	98%
T3359	Aprotinin a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, ...
T20992	MEGA-9	85261-19-4	98%
T20992	MEGA-9 solubilizes membrane protein and can be used as a nonionic detergent.
T6370	AEBSF hydrochloride	30827-99-7	98%
T6370	AEBSF hydrochloride is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.
TP1792L	KKI-5 acetate(97145-43-2 free base)	TP1792L	98%
TP1792L	KKI-5 acetate is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as ...
T13408	ZK824190	2254001-81-3	98%
T13408	ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 16...
T6564	Leupeptin Hemisulfate	103476-89-7	98%
T6564	Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.
T3990	AA26-9	1312782-34-5	98%
T3990	AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.
T3442	UK-371804	256477-09-5	98%
T3442	UK-371804 is an effective and specific uPA inhibitor. It was selected as a candidate for further preClinicalal evaluation for the treatment of chronic dermal ulc...
T3S0381	Chrysophanol 8-O-glucoside	13241-28-6	98%
T3S0381	Chrysophanol 8-O-glucoside and chrysophanol have mild cytotoxicity and anti-diabetic properties and can play metabolic roles in the insulin-stimulated glucose tr...
T2392	Nafamostat mesylate	82956-11-4	98%
T2392	Nafamostat mesylate, a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic de...
T5597	ZT-12-037-01	2328073-61-4	98%
T5597	Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).
TN1372	Alpha-Amyrin	638-95-9	98%
TN1372	Alpha-Amyrin is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepatomodulatory.
T25549	JCP174	126062-19-9	98%
T25549	JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1.
T12613L	BAY-85-8501	1161921-82-9	98%
T12613L	BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)
TN1022	Secologanoside	59472-23-0	98%
TN1022	Secologanoside shows anti-complementary, allelopathic, and anti-elastase activities.
T6285	GSK-690693	937174-76-0	98%
T6285	GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
T1145	Diminazene Aceturate	908-54-3	98%
T1145	Diminazene is a trypanocidal agent.