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TRP/TRPV Channel

TRPV is a family of transient receptor potential cation channels (TRP channels) in animals. All TRPVs are highly calcium selective. TRP channels are a large group of ion channels consisting of six protein families, located mostly on the plasma membrane of numerous human and animal cell types, and in some fungi.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T16763 RN-1747 1024448-59-6 98%
RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: 0.77 μM, 4.0 μM, and 4.1 μM for hTRPV4, mTRPV4, and rTRPV...
T28548 RN9893 1803003-68-0 98%
RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.
T1109 (Z)-Capsaicin 25775-90-0 98%
Zucapsaicin is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.Zucapsaicin is a synthetic cis isomer of natural capsaicin that ...
T0457 Probenecid 57-66-9 98%
Probenecid is a benzoic acid derivative with antihyperuricemic property.
T34081 Piromelatine 946846-83-9 98%
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibito...
T7177 Capsazepine 138977-28-3 98%
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of c...
T2952 Camphor 76-22-2 98%
Camphor is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and as an anti-infec...
T2845 Imperatorin 482-44-0 98%
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T0851 Pregnenolone 145-13-1 98%
Pregnenolone is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
T1622 Rosiglitazone maleate 155141-29-0 98%
Rosiglitazone Maleate is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity...
T7572 RN-1734 946387-07-1 98%
RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)
T5786 TETRAHYDROPIPERINE 23434-88-0 98%
TETRAHYDROPIPERINE is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.
T0334 Rosiglitazone 122320-73-4 98%
Rosiglitazone is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Rosiglitazone has been linked to rare...
T12849 SAR7334 1333210-07-3 98%
SAR7334 is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).
TN1377 α-Spinasterol 481-18-5 98%
α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α...
T6977 SB-366791 472981-92-3 98%
SB-366791 is a new and selective cinnamide TRPV1 antagonist.
T2007 RQ-00203078 1254205-52-1 98%
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
T10247 Adenosine 5'-diphosphoribose sodium 68414-18-6 98%
Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a metabolite of nicotinamide adenine nucleotide (NAD+), which is widely present in organisms.Adenosine...
T72662 NMDAR/TRPM4-IN-2 2243506-33-2 98%
NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retina...
T8562 A 425619 581809-67-8 98%
A 425619 is a potent TRPV1 antagonist
RN-1747
T16763
RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: 0.77 μM, 4.0 μM, and 4.1 μM for hTRPV4, mTRPV4, and rTRPV...
RN9893
T28548
RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.
(Z)-Capsaicin
T1109
Zucapsaicin is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.Zucapsaicin is a synthetic cis isomer of natural capsaicin that ...
Probenecid
T0457
Probenecid is a benzoic acid derivative with antihyperuricemic property.
Piromelatine
T34081
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibito...
Capsazepine
T7177
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of c...
Camphor
T2952
Camphor is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and as an anti-infec...
Imperatorin
T2845
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
Pregnenolone
T0851
Pregnenolone is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
Rosiglitazone maleate
T1622
Rosiglitazone Maleate is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity...
RN-1734
T7572
RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)
TETRAHYDROPIPERINE
T5786
TETRAHYDROPIPERINE is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.
Rosiglitazone
T0334
Rosiglitazone is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Rosiglitazone has been linked to rare...
SAR7334
T12849
SAR7334 is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).
α-Spinasterol
TN1377
α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α...
SB-366791
T6977
SB-366791 is a new and selective cinnamide TRPV1 antagonist.
RQ-00203078
T2007
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
Adenosine 5'-diphosphoribose sodium
T10247
Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a metabolite of nicotinamide adenine nucleotide (NAD+), which is widely present in organisms.Adenosine...
NMDAR/TRPM4-IN-2
T72662
NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retina...
A 425619
T8562
A 425619 is a potent TRPV1 antagonist
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