T16763 |
RN-1747
|
1024448-59-6
|
98%
|
|
RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: 0.77 μM, 4.0 μM, and 4.1 μM for hTRPV4, mTRPV4, and rTRPV...
|
T28548 |
RN9893
|
1803003-68-0
|
98%
|
|
RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.
|
T1109 |
(Z)-Capsaicin
|
25775-90-0
|
98%
|
|
Zucapsaicin is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.Zucapsaicin is a synthetic cis isomer of natural capsaicin that ...
|
T0457 |
Probenecid
|
57-66-9
|
98%
|
|
Probenecid is a benzoic acid derivative with antihyperuricemic property.
|
T34081 |
Piromelatine
|
946846-83-9
|
98%
|
|
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibito...
|
T7177 |
Capsazepine
|
138977-28-3
|
98%
|
|
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of c...
|
T2952 |
Camphor
|
76-22-2
|
98%
|
|
Camphor is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and as an anti-infec...
|
T2845 |
Imperatorin
|
482-44-0
|
98%
|
|
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
|
T0851 |
Pregnenolone
|
145-13-1
|
98%
|
|
Pregnenolone is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.
|
T1622 |
Rosiglitazone maleate
|
155141-29-0
|
98%
|
|
Rosiglitazone Maleate is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity...
|
T7572 |
RN-1734
|
946387-07-1
|
98%
|
|
RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)
|
T5786 |
TETRAHYDROPIPERINE
|
23434-88-0
|
98%
|
|
TETRAHYDROPIPERINE is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.
|
T0334 |
Rosiglitazone
|
122320-73-4
|
98%
|
|
Rosiglitazone is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Rosiglitazone has been linked to rare...
|
T12849 |
SAR7334
|
1333210-07-3
|
98%
|
|
SAR7334 is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).
|
TN1377 |
α-Spinasterol
|
481-18-5
|
98%
|
|
α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α...
|
T6977 |
SB-366791
|
472981-92-3
|
98%
|
|
SB-366791 is a new and selective cinnamide TRPV1 antagonist.
|
T2007 |
RQ-00203078
|
1254205-52-1
|
98%
|
|
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
|
T10247 |
Adenosine 5'-diphosphoribose sodium
|
68414-18-6
|
98%
|
|
Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a metabolite of nicotinamide adenine nucleotide (NAD+), which is widely present in organisms.Adenosine...
|
T72662 |
NMDAR/TRPM4-IN-2
|
2243506-33-2
|
98%
|
|
NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retina...
|
T8562 |
A 425619
|
581809-67-8
|
98%
|
|
A 425619 is a potent TRPV1 antagonist
|