Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
説明 | (E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors. |
In vitro | (E)-GABAB receptor antagonist 1 reduces the maximum effect of IP3 in HEK293 cells overexpressing GABAB receptor and Gqi9 protein induced by agonist GABA, but does not alter EC50[1]. |
分子量 | 304.38 |
分子式 | C18H24O4 |
CAS No. | 1611483-29-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (164.27 mM)
You can also refer to dose conversion for different animals. 詳細
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(E)-GABAB receptor antagonist 1 1611483-29-4 Membrane transporter/Ion channel Neuroscience GABA Receptor (E) GABAB receptor antagonist 1 (E)GABAB receptor antagonist 1 GABAB receptor antagonist 1 Inhibitor inhibitor inhibit