Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.
説明 | (E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator. |
ターゲット&IC50 | HCT116 cells:41.59 μM , HCT116 cells:43.02 μM |
In vitro | (E)-[6]-Dehydroparadol (5-80 µM; 24 h) inhibits the growth of HCT-116 and H-1299 cells, with IC50s of 43.02 and 41.59 µM, respectively. (E)-[6]-Dehydroparadol (10-40 µM; 24 h) induces apoptosis in HCT-116 and H-1299 cells[1]. |
In vivo | (E)-[6]-Dehydroparadol at a concentration of 5 µM for 24 hours increases the fluorescence signal of Tg[glutathione S-transferase pi 1 (gstp1):green fluorescent protein (GFP)] in Tg(gstp1:GFP) transgenic zebrafish embryos. |
別名 | (6)-Dehydroparadol |
分子量 | 276.37 |
分子式 | C17H24O3 |
CAS No. | 878006-06-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 120 mg/mL (434.2 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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(E)-[6]-Dehydroparadol 878006-06-5 Immunology/Inflammation Nrf2 [6]-Dehydroparadol (6)-Dehydroparadol Inhibitor inhibitor inhibit